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Transcription Factor TFIIIB

Known as: TFIIIB, Transcription Factor, Transcription Factor IIIB, TFIIIB 
One of several general transcription factors that are specific for RNA POLYMERASE III. TFIIIB recruits and positions pol III over the initiation site… Expand
National Institutes of Health

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BDP1 protein, human
BRF1 protein, humanBRF2 protein, humanBasal transcription factor genesDNA-Binding Proteins
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Papers overview

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Highly Cited
2003
Highly Cited
2003
Direct activation of RNA polymerase III transcription by c-Myc
The proto-oncogene product c-Myc has a direct role in both metazoan cell growth and division. RNA polymerase III (pol III) is… Expand
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Highly Cited
2003
Highly Cited
2003
p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB
The tumor suppressor p53 is a transcription factor that controls cellular growth and proliferation. p53 targets include RNA… Expand
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Highly Cited
2002
Highly Cited
2002
A unified nomenclature for TATA box binding protein (TBP)-associated factors (TAFs) involved in RNA polymerase II transcription.
  • L. Tora
  • Genes & development
  • 2002
    • Corpus ID: 35269609
Initiation of transcription by RNA polymerase II (Pol II) requires general transcription factors to assemble the Pol II pre… Expand
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Highly Cited
2000
Highly Cited
2000
Different human TFIIIB activities direct RNA polymerase III transcription from TATA-containing and TATA-less promoters.
Transcription initiation at RNA polymerase III promoters requires transcription factor IIIB (TFIIIB), an activity that binds to… Expand
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Highly Cited
1999
Highly Cited
1999
CoREST: a functional corepressor required for regulation of neural-specific gene expression.
Several genes encoding proteins critical to the neuronal phenotype, such as the brain type II sodium channel gene, are expressed… Expand
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Review
1996
Review
1996
The SANT domain: a putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB.
 
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Highly Cited
1992
Highly Cited
1992
The role of the TATA-binding protein in the assembly and function of the multisubunit yeast RNA polymerase III transcription factor, TFIIIB
The Saccharomyces cerevisiae RNA polymerase III transcription factor (TF)IIIB has been assembled from three components. An… Expand
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Highly Cited
1992
Highly Cited
1992
A TBP complex essential for transcription from TATA-less but not TATA-containing RNA polymerase III promoters is part of the TFIIB fraction
The TATA box-binding protein TBP directs transcription by all three eukaryotic RNA polymerases. In mammalian cells, TBP is found… Expand
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Highly Cited
1990
Highly Cited
1990
S. cerevisiae TFIIIB is the transcription initiation factor proper of RNA polymerase III, while TFIIIA and TFIIIC are assembly factors
The S. cerevisiae RNA polymerase III (pol III) transcription factor TFIIIB binds to DNA upstream of the transcription start site… Expand
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Highly Cited
1989
Highly Cited
1989
Transcription factor IIIB generates extended DNA interactions in RNA polymerase III transcription complexes on tRNA genes.
Transcription complexes that assemble on tRNA genes in a crude Saccharomyces cerevisiae cell extract extend over the entire… Expand
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