Transcription Factor TFIIIB

Known as: TFIIIB, Transcription Factor, Transcription Factor IIIB, TFIIIB 
One of several general transcription factors that are specific for RNA POLYMERASE III. TFIIIB recruits and positions pol III over the initiation site… (More)
National Institutes of Health

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BDP1 protein, human
BRF1 protein, humanBRF2 protein, humanBasal transcription factor genesDNA-Binding Proteins
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Papers overview

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Highly Cited
2010
Highly Cited
2010
Genomic Binding Profiles of Functionally Distinct RNA Polymerase III Transcription Complexes in Human Cells
Genome-wide occupancy profiles of five components of the RNA polymerase III (Pol III) machinery in human cells identified the… (More)
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2008
2008
PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex.
PTEN, a tumor suppressor whose function is frequently lost in human cancers, possesses a lipid phosphatase activity that… (More)
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Highly Cited
2003
Highly Cited
2003
Direct activation of RNA polymerase III transcription by c-Myc
The proto-oncogene product c-Myc has a direct role in both metazoan cell growth and division. RNA polymerase III (pol III) is… (More)
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Highly Cited
2003
Highly Cited
2003
p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB.
The tumor suppressor p53 is a transcription factor that controls cellular growth and proliferation. p53 targets include RNA… (More)
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Highly Cited
1998
Highly Cited
1998
Rapamycin induces the G0 program of transcriptional repression in yeast by interfering with the TOR signaling pathway.
The macrolide antibiotic rapamycin inhibits cellular proliferation by interfering with the highly conserved TOR (for target of… (More)
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Highly Cited
1998
Highly Cited
1998
p53 is a general repressor of RNA polymerase III transcription.
p53 is a major tumour suppressor that is inactivated in a large proportion of human cancers. We show that p53 serves as a general… (More)
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Highly Cited
1995
Highly Cited
1995
Requirement of RNA polymerase III transcription factors for in vitro position-specific integration of a retroviruslike element.
The yeast retroviruslike element Ty3 inserts at the transcription initiation sites of genes transcribed by RNA polymerase III… (More)
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1992
1992
The TATA-binding protein and associated factors are components of pol III transcription factor TFIIIB
RNA polymerases I, II, and III require the TATA-binding protein (TBP) to initiate promoter-specific transcription. We have… (More)
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1991
1991
Two essential components of the Saccharomyces cerevisiae transcription factor TFIIIB: transcription and DNA-binding properties.
RNA polymerase III transcription factor TFIIIB from Saccharomyces cerevisiae contains at least two polypeptides, with apparent… (More)
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Highly Cited
1990
Highly Cited
1990
S. cerevisiae TFIIIB is the transcription initiation factor proper of RNA polymerase III, while TFIIIA and TFIIIC are assembly factors
The S. cerevisiae RNA polymerase III (pol III) transcription factor TFIIIB binds to DNA upstream of the transcription start site… (More)
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