Transcription Factor TFIIB

Known as: TFIIB, Transcription Factor IIB, Transcription Factor TFIIB [Chemical/Ingredient] 
An RNA POLYMERASE II specific transcription factor. It plays a role in assembly of the pol II transcriptional preinitiation complex and has been… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Previous x-ray crystal structures have given insight into the mechanism of transcription and the role of general transcription… (More)
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Highly Cited
2009
Highly Cited
2009
To initiate gene transcription, RNA polymerase II (Pol II) requires the transcription factor IIB (B). Here we present the crystal… (More)
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Highly Cited
2004
Highly Cited
2004
The structure of the general transcription factor IIB (TFIIB) in a complex with RNA polymerase II reveals three features crucial… (More)
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Highly Cited
2000
Highly Cited
2000
The human vitamin D receptor (hVDR) is a ligand-regulated transcription factor that mediates the actions of the 1,25… (More)
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Highly Cited
1994
Highly Cited
1994
THE transcription factor CREB binds to a DNA element known as the cAMP-regulated enhancer (CRE)1–5. CREB is activated through… (More)
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Highly Cited
1993
Highly Cited
1993
Enhancement of RNA polymerase II transcription by the viral transactivator VP16 requires the TFIID complex, which consists of the… (More)
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Highly Cited
1993
Highly Cited
1993
How eukaryotic promoter-specific activator proteins (activators) stimulate transcription is a central question. We have… (More)
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Highly Cited
1993
Highly Cited
1993
The retinoblastoma (RB) tumor suppressor protein and the TATA-box-binding protein TFIID form contacts with a number of viral… (More)
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Highly Cited
1993
Highly Cited
1993
The human thyroid hormone receptor beta (hTR beta) is capable of both transcriptional silencing and hormone-dependent activation… (More)
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Highly Cited
1991
Highly Cited
1991
A CENTRAL issue in eukaryotic transcriptional regulation is the mechanism by which promoter-specific transcription factors… (More)
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