Transcription Factor CHOP

Known as: Homologous Protein, C-EBP, DNA Damage-Inducible Transcript 3 Protein, C/EBP-Homologous Protein 10 
DNA damage-inducible transcript 3 protein (169 aa, ~19 kDa) is encoded by the human DDIT3 gene. This protein plays a role in the sequestration of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2018
0204019852018

Papers overview

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Highly Cited
2012
Highly Cited
2012
Endoplasmic reticulum (ER) stress-induced apoptosis has been implicated in various neurodegenerative diseases including Parkinson… (More)
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Highly Cited
2008
Highly Cited
2008
The endoplasmic reticulum (ER) is an important site for protein folding and becomes "stressed" when its capacity to fold proteins… (More)
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Highly Cited
2008
Highly Cited
2008
CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) is a key component in endoplasmic reticulum (ER) stress-mediated… (More)
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Highly Cited
2008
Highly Cited
2008
Data concerning the fine structure of the 12q13-15 amplicon which contains MDM2 and CDK4 in well-differentiated and… (More)
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Highly Cited
2006
Highly Cited
2006
Increased lipid supply causes beta cell death, which may contribute to reduced beta cell mass in type 2 diabetes. We investigated… (More)
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Highly Cited
2004
Highly Cited
2004
AbstractWe reported that the endoplasmic reticulum (ER) stress pathway involving CHOP, a member of the C/EBP transcription factor… (More)
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Highly Cited
2001
Highly Cited
2001
CHOP/gadd153 is a transcription factor induced by cellular stresses such as UV light, genotoxic agents, and protein misfolding in… (More)
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Highly Cited
1998
Highly Cited
1998
CHOP (GADD153) is a small nuclear protein that dimerizes avidly with members of the C/EBP family of transcription factors… (More)
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Highly Cited
1996
Highly Cited
1996
CHOP (GADD153) is a member of the C/EBP family and a stress-induced protein. To investigate the role of CHOP in cellular growth… (More)
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Highly Cited
1992
Highly Cited
1992
We report on the identification of a nuclear protein that serves as a dominant-negative inhibitor of the transcription factors C… (More)
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