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Transcription Factor AP-2 Alpha

Known as: AP 2 alpha Protein, AP2, AP-2-Alpha 
Transcription factor AP-2-alpha (437 aa, ~48 kDa) is encoded by the human TFAP2A gene. This protein plays a role in both transcriptional regulation… 
National Institutes of Health

Related topics

Related topics

14 relations
AP2A1 geneAntifibrinolytic AgentsCaspase Cascade PathwayCell Nucleus

Broader (1)

enhancer-binding protein AP-2

Papers overview

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2009
2009
Fragile histidine triad protein, WW domain‐containing oxidoreductase protein Wwox, and activator protein 2γ expression levels correlate with basal phenotype in breast cancer
The expression of fragile histidine triad protein (Fhit) and WW domain‐containing oxidoreductase protein (Wwox), tumor… 
Highly Cited
2005
Highly Cited
2005
Role of mitogen-activated protein kinase pathway in reactive oxygen species-mediated endothelin-1-induced beta-myosin heavy chain gene expression and cardiomyocyte hypertrophy.
Endothelin-1 (ET-1) has been found to increase cardiac beta-myosin heavy chain (beta-MyHC) gene expression and induce hypertrophy… 
Highly Cited
2005
Highly Cited
2005
Ultraviolet A-induced signaling involves a ceramide-mediated autocrine loop leading to ceramide de novo synthesis.
Exposure of human keratinocytes to ultraviolet A (UVA) radiation at physiological doses leads to a biphasic activation of… 
Highly Cited
2004
Highly Cited
2004
Skeletal and pigment cell defects in the lockjaw mutant reveal multiple roles for zebrafish tfap2a in neural crest development
Members of the AP‐2 transcription factor family have critical roles in many aspects of embryonic development. The zebrafish… 
Highly Cited
2001
Highly Cited
2001
Transcriptional activation of the human HMG1 gene in cisplatin-resistant human cancer cells.
The nonhistone chromosomal protein, high mobility group 1 (HMG1), which is ubiquitously expressed in higher eukaryotic cells… 
1999
1999
Ksp-cadherin gene promoter. I. Characterization and renal epithelial cell-specific activity.
Kidney-specific cadherin (Ksp-cadherin, cadherin 16) is a novel, kidney-specific member of the cadherin superfamily that is… 
Highly Cited
1998
Highly Cited
1998
Transcriptional regulation of human adrenomedullin gene in vascular endothelial cells.
Adrenomedullin (AM) is a recently identified vasodilator peptide produced in cardiovascular organs such as the heart, vascular… 
Highly Cited
1992
Highly Cited
1992
Structural characterization of the 5' regions of the human phenylalanine hydroxylase gene.
Human phenylalanine hydroxylase (PAH) is expressed in a liver-specific manner and catalyzes the enzymatic conversion of… 
Highly Cited
1990
Highly Cited
1990
Nuclear factor-I and activator protein-2 bind in a mutually exclusive way to overlapping promoter sequences and trans-activate the human growth hormone gene
Transcription of the human growth hormone (hGH) gene and its regulation are controlled by trans-acting factors that bind to hGH… 
Highly Cited
1989
Highly Cited
1989
Hepatitis B virus X gene activates kappa B-like enhancer sequences in the long terminal repeat of human immunodeficiency virus 1.
The role of the hepatitis B virus (HBV) X gene during virus infection has not been defined. We previously showed that expression… 
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