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Transcription Activator-Like Effector Nucleases

Known as: Transcription Activator-Like Effector Nucleases [Chemical/Ingredient], Nucleases, Transcription Activator Like Effector, TALENs 
Artificial nucleases that cleave DNA at a defined distance from specific DNA sequences recognized by TRANSCRIPTION ACTIVATOR-LIKE EFFECTORS. They are… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Abstract Gene therapy has long held promise to correct a variety of human diseases and defects. Discovery of the Clustered… Expand
Review
2018
Review
2018
The availability of genome sequences for several crops and advances in genome editing approaches has opened up possibilities to… Expand
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Review
2018
Review
2018
Genome editing technologies have progressed rapidly and become one of the most important genetic tools in the implementation of… Expand
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Review
2014
Review
2014
Programmable nucleases — including zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and RNA… Expand
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Highly Cited
2012
Highly Cited
2012
The ability to precisely engineer plant genomes offers much potential for advancing basic and applied plant biology. Here, we… Expand
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Highly Cited
2012
Highly Cited
2012
Transcription activator-like effector nucleases (TALENs) are an approach for directed gene disruption and have been proved to be… Expand
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Highly Cited
2011
Highly Cited
2011
TALENs are important new tools for genome engineering. Fusions of transcription activator-like (TAL) effectors of plant… Expand
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Highly Cited
2011
Highly Cited
2011
Sequence-specific nucleases represent valuable tools for precision genome engineering. Traditionally, zinc-finger nucleases (ZFNs… Expand
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Highly Cited
2011
Highly Cited
2011
DNA double-strand breaks enhance homologous recombination in cells and have been exploited for targeted genome editing through… Expand
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Highly Cited
2003
Highly Cited
2003
Hundreds of small RNAs of ∼22 nucleotides, collectively named microRNAs (miRNAs), have been discovered recently in animals and… Expand
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