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Toxic Epidermal Necrolysis

Known as: Epidermal Necrolysis, Toxic, NECROLYSIS, TOXIC EPIDERMAL, Nonstaphylococcal Scalded Skin Syndrome 
A systemic, serious, and life-threatening disorder characterized by erythematous and necrotic lesions in the skin and mucous membranes that are… 
National Institutes of Health

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Related topics

6 relations
Dermatologic disordersExfoliative dermatitisIntegumentary systemSkin
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Highly Cited
2008
Highly Cited
2008
Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study.
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe cutaneous adverse reactions (SCAR… 
Highly Cited
2008
Highly Cited
2008
Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening adverse drug reactions characterized by… 
Highly Cited
2008
Highly Cited
2008
A European study of HLA-B in Stevens–Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugs
Background Stevens–Johnson syndrome (SJS) and its severe form, toxic epidermal necrolysis (TEN), are rare but life-threatening… 
Review
2003
Review
2003
Oxidative DNA damage: mechanisms, mutation, and disease
Oxidative DNA damage is an inevitable consequence of cellular metabolism, with a propensity for increased levels following toxic… 
Review
2002
Review
2002
Correlations between clinical patterns and causes of erythema multiforme majus, Stevens-Johnson syndrome, and toxic epidermal necrolysis: results of an international prospective study.
BACKGROUND It was proposed that Stevens-Johnson syndrome and toxic epidermal necrolysis differed from erythema multiforme majus… 
Highly Cited
2000
Highly Cited
2000
SCORTEN: a severity-of-illness score for toxic epidermal necrolysis.
The mortality of toxic epidermal necrolysis is about 30%. Our purpose was to develop and validate a specific severity-of-illness… 
Highly Cited
1998
Highly Cited
1998
Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin.
Toxic epidermal necrolysis (TEN, Lyell's syndrome) is a severe adverse drug reaction in which keratinocytes die and large… 
Review
1993
Review
1993
Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme.
BACKGROUND AND DESIGN To conduct a prospective case-control study about causative factors of severe bullous erythema multiforme… 
Review
1990
Review
1990
Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic…
  • S. Safe
  • Critical reviews in toxicology
  • 1990
  • Corpus ID: 27477203
Halogenated aromatic compounds, typified by the polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), biphenyls (PCBs… 
Highly Cited
1956
Highly Cited
1956
TOXIC EPIDERMAL NECROLYSIS: AN ERUPTION RESEMBLING SCALDING OF THE SKIN.
  • A. Lyell
  • The British journal of dermatology
  • 1956
  • Corpus ID: 20177120
THE purpose of this paper is to describe the course of events in four cases of a toxic ertiption which closely resembles scalding… 
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