FAQ

Toxic Epidermal Necrolysis

Known as: Epidermal Necrolysis, Toxic, Necrolysis, Toxic Epidermal, Nonstaphylococcal Scalded Skin Syndrome 
A systemic, serious, and life-threatening disorder characterized by erythematous and necrotic lesions in the skin and mucous membranes that are… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1947-2018
010020030019472017

Related topics

Related topics

8 relations
Dermatologic disordersExfoliative dermatitisIntegumentary systemPediatric Adverse Events Terminology
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Toxic Epidermal Necrolysis
Dermatologic disorders
Skin
Stevens-Johnson Syndrome
Exfoliative dermatitis
Integumentary system

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening adverse drug reactions characterized by… (More)
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Highly Cited
2008
Highly Cited
2008
A European study of HLA-B in Stevens-Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugs.
BACKGROUND Stevens-Johnson syndrome (SJS) and its severe form, toxic epidermal necrolysis (TEN), are rare but life-threatening… (More)
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Highly Cited
2008
Highly Cited
2008
Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study.
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe cutaneous adverse reactions (SCAR… (More)
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Highly Cited
2002
Highly Cited
2002
Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome
The term toxic epidermal necrolysis (TEN) was introduced in 1956 by Lyell to describe four patients with a syndrome featured by… (More)
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Highly Cited
2000
Highly Cited
2000
SCORTEN: a severity-of-illness score for toxic epidermal necrolysis.
The mortality of toxic epidermal necrolysis is about 30%. Our purpose was to develop and validate a specific severity-of-illness… (More)
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Highly Cited
1998
Highly Cited
1998
Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin.
Toxic epidermal necrolysis (TEN, Lyell's syndrome) is a severe adverse drug reaction in which keratinocytes die and large… (More)
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1997
1997
Plasmapheresis in toxic epidermal necrolysis.
BACKGROUND The treatment of toxic epidermal necrolysis (TEN) is usually based on the removal of the offending drug(s), fluid… (More)
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1996
1996
Toxic epidermal necrolysis.
BACKGROUND Most studies on drug-induced toxic epidermal necrolysis (TEN) report a high mortality rate. This has been attributed… (More)
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Highly Cited
1995
Highly Cited
1995
Medication use and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis.
BACKGROUND Toxic epidermal necrolysis and Stevens-Johnson syndrome are rare, life-threatening, drug-induced cutaneous reactions… (More)
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1987
1987
Genetic susceptibility to toxic epidermal necrolysis.
The pathophysiologic events leading to toxic epidermal necrolysis (TEN) remain unknown. With the idea of an immunologically… (More)
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