Toremifene

Known as: Toremifenum, (Z)-2-[4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine, TOR 
A nonsteroidal triphenylethylene antiestrogen. Chemically related to tamoxifen, toremifene is a selective estrogen receptor modulator (SERM). This… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
PURPOSE Androgen deprivation therapy is associated with fracture risk in men with prostate cancer. We assessed the effects of… (More)
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Review
2009
Review
2009
Research on TOR has grown exponentially during the last decade, generating a complex model of the TOR signaling network… (More)
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Highly Cited
2008
Highly Cited
2008
We tested a hypothesis that activation of growth-promoting pathways is required for cellular senescence. In the presence of serum… (More)
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Highly Cited
2007
Highly Cited
2007
TOR (Target of Rapamycin) is a highly conserved protein kinase and a central controller of cell growth. TOR is found in two… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE A randomized, double-blind, dose finding, placebo controlled, parallel group clinical study was done to determine the… (More)
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Highly Cited
2005
Highly Cited
2005
Dictyostelium cells form a multicellular organism through the aggregation of independent cells. This process requires both… (More)
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Highly Cited
1999
Highly Cited
1999
Rapamycin inhibits the TOR kinases, which regulate cell proliferation and mRNA translation and are conserved from yeast to man… (More)
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Highly Cited
1999
Highly Cited
1999
Tor proteins, homologous to DNA-dependent protein kinases, participate in a signal transduction pathway in yeast that regulates… (More)
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Highly Cited
1993
Highly Cited
1993
The hepatoproliferative effects of 2 antiestrogens, tamoxifen and toremifene, were compared in a sequential 15-month study in… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND Antiestrogens inhibit the stimulative effects of estrogens on breast cancer growth, but the mechanism(s) by which they… (More)
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