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Toremifene

Known as: Toremifenum, (Z)-2-[4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine, TOR 
A nonsteroidal triphenylethylene antiestrogen. Chemically related to tamoxifen, toremifene is a selective estrogen receptor modulator (SERM). This… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Research on TOR has grown exponentially during the last decade, generating a complex model of the TOR signaling network… Expand
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Highly Cited
2008
Highly Cited
2008
We tested a hypothesis that activation of growth-promoting pathways is required for cellular senescence. In the presence of serum… Expand
Highly Cited
2007
Highly Cited
2007
TOR (Target of Rapamycin) is a highly conserved protein kinase and a central controller of cell growth. TOR is found in two… Expand
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Highly Cited
2005
Highly Cited
2005
The removal of extracellular amino acids or leucine alone inhibits the ability of the mammalian target of rapamycin (mTOR) to… Expand
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Highly Cited
2003
Highly Cited
2003
The highly conserved Tor kinases (TOR) and the protein kinase A (PKA) pathway regulate cell proliferation in response to growth… Expand
Review
2002
Review
2002
  • P. Seeman
  • Canadian journal of psychiatry. Revue canadienne…
  • 2002
  • Corpus ID: 14930109
Background: Al though the prin ci pal brain tar get that all an tipsy chotic drugs at tach to is the do pamine D2 re cep tor, tra… Expand
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Highly Cited
1999
Highly Cited
1999
Rapamycin inhibits the TOR kinases, which regulate cell proliferation and mRNA translation and are conserved from yeast to man… Expand
Highly Cited
1999
Highly Cited
1999
Tor proteins, homologous to DNA‐dependent protein kinases, participate in a signal transduction pathway in yeast that regulates… Expand
Review
1998
Review
1998
Much remains to be discovered about the many roles of the auxiliary proteins of HIV-1 in the viral life cycle, and the list of… Expand
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Highly Cited
1993
Highly Cited
1993
The hepatoproliferative effects of 2 antiestrogens, tamoxifen and toremifene, were compared in a sequential 15-month study in… Expand
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