Topoisomerase I Inhibitor LMP776

Known as: LMP776 
An indenoisoquinoline and non-camptothecin inhibitor of topoisomerase I (Top I) with potential antineoplastic activity. Topoisomerase I inhibitor… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2012-2016
01220122016

Papers overview

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2016
2016
An HPLC method for the assay of a DNA topoisomerase inhibitor, LMP776 (NSC 725776), has been developed and validated. The stress… (More)
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2014
2014
  • Yuko Maede, Hiroyasu Shimizu, +6 authors Junko Murai
  • Molecular cancer therapeutics
  • 2014
Clinical topoisomerase I (Top1) and II (Top2) inhibitors trap topoisomerases on DNA, thereby inducing protein-linked DNA breaks… (More)
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2014
2014
Carbohydrate moieties were strategically transported from the indolocarbazole topoisomerase I (Top1) inhibitor class to the… (More)
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2012
2012
Hydroxylated analogues of the anticancer topoisomerase I (Top1) inhibitors indotecan (LMP400) and indimitecan (LMP776) have been… (More)
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