Tonic-Clonic Epilepsy

Known as: PRIMARY GENERALIZED EPILEPSY, MAJOR, Tonic-Clonic Convulsion Syndromes, Tonic-Clonic Convulsion Disorder 
A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
INTRODUCTION Primary generalized tonic clonic seizures (pGTCS) are still linked to major concerns for the clinic and hazards for… (More)
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Review
2011
Review
2011
Sudden unexpected death in epilepsy (SUDEP) refers to the sudden death of a seemingly healthy individual with epilepsy, usually… (More)
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Highly Cited
2009
Highly Cited
2009
Generalized tonic-clonic seizures are among the most dramatic physiological events in the nervous system. The brain regions… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVES To determine the prevalence of cognitive delay and possible associated dysmorphic features in children exposed to… (More)
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Highly Cited
2003
Highly Cited
2003
Neuroactive steroids are potent modulators of gamma-aminobutyric acid type A receptors (GABAARs), and their behavioral effects… (More)
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Highly Cited
2001
Highly Cited
2001
Severe myoclonic epilepsy of infancy (SMEI) is a rare disorder that occurs in isolated patients. The disease is characterized by… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND AND OBJECTIVE Topiramate is effective as adjunctive treatment of partial-onset seizures in adults. The efficacy and… (More)
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Highly Cited
1996
Highly Cited
1996
1. To investigate the origin and functional significance of a recently described tonic GABAA receptor-mediated conductance in… (More)
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Highly Cited
1994
Highly Cited
1994
We studied 120 generalized tonic-clonic seizures (GTCSs) in 47 patients with video-EEG telemetry. GTCSs were preceded by… (More)
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Highly Cited
1993
Highly Cited
1993
In order to more precisely define a syndrome of medial temporal lobe epilepsy, histories and physical findings were evaluated in… (More)
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