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Tolazamide

Known as: N-(P-Toluenesulfonyl)-n'-hexamethyleniminourea, Tolazamidum, 1-(hexahydro-1-Azepinyl)-3-P-tolylsulfonylurea 
An intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. Tolazamide is converted into five major metabolites that are… 
National Institutes of Health

Related topics

Related topics

15 relations
Diabetes Mellitus, Non-Insulin-DependentIn BloodPregnancySulfonylurea Compounds

Broader (1)

Hypoglycemic Agents

Narrower (1)

Tolinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1989
1989
Sulfonylurea binding to adipocyte membranes and potentiation of insulin-stimulated hexose transport.
1985
1985
Effect of sulfonylurea therapy on plasma lipids and high-density lipoprotein composition in non-insulin-dependent diabetes mellitus.
1984
1984
Lichenoid drug reactions to chlorpropamide and tolazamide.
Many medications, including gold, antimalarials, quinidine, and thiazide diuretics have been implicated in lichenoid drug… 
1983
1983
Extrapancreatic action of sulfonylureas: hypoglycemic effects are not dependent on altered insulin binding or inhibition of transglutaminase.
1983
1983
Wernicke's encephalopathy induced by tolazamide.
THE Wernicke–Korsakoff syndrome is a nutritional neurologic disorder that is due to thiamine deficiency. Although Wernicke's… 
1980
1980
Pseudoinsulinoma syndrome from inadvertent tolazamide ingestion.
A 70-year-old woman with rheumatoid arthritis presented with fasting hypoglycemia, inappropriately elevated insulin and C-peptide… 
1980
1980
Impaired Granulocyte Adherence in Mildly Diabetic Patients: Effects of Tolazamide Treatment
Granulocyte adherence in 10 of 15 untreated asymptomatic hyperglycemic diabetic outpatients (mean fasting glucose ± SEM, 289 ± 16… 
Review
1978
Review
1978
Oral hypoglycemic agent update.
1971
1971
GC determination of tolazamide in plasma.
A highly specific, sensitive, GC method for the determination of tolazamide is described. The lower limit of detection… 
1956
1956
Ineffectiveness of Sulfonylureas in Alloxan Diabetic Rats.∗
Summary Oral administration of 100 mg 1-3-butyl-p-tolylsulfonylurea per kg body weight to normal rats results in a marked… 
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