Tolazamide

Known as: N-(P-Toluenesulfonyl)-n'-hexamethyleniminourea, Tolazamidum, 1-(hexahydro-1-Azepinyl)-3-P-tolylsulfonylurea 
An intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. Tolazamide is converted into five major metabolites that are… (More)
National Institutes of Health

Related topics

Related topics

15 relations
Diabetes Mellitus, Non-Insulin-DependentIn BloodPregnancySulfonylurea Compounds
(More)

Broader (1)

Hypoglycemic Agents

Narrower (1)

Tolinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
BRAND LOYALTY , ENTRY , AND PRICE COMPETITION IN PHARMACEUTICALS AFTER THE 1984 DRUG ACT *
Your use of the JSTOR archive indicates your acceptance of JSTOR's Terms and Conditions of Use, available at http://www.jstor.org… (More)
  • table 1
  • figure 1
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Individual sulfonylureas and serious hypoglycemia in older people.
OBJECTIVE To compare the risk of serious hypoglycemia associated with the use of individual sulfonylureas in older people… (More)
Is this relevant?
1993
1993
A species comparison of tolbutamide metabolism in precision-cut liver slices from rats and dogs. Qualitative and quantitative sex differences.
Precision-cut liver slices from rats and dogs were used to investigate in vitro the metabolism of tolbutamide. Tolbutamide (100… (More)
Is this relevant?
1987
1987
Effects of tolazamide and exogenous insulin on pattern of postprandial carbohydrate metabolism in patients with non-insulin-dependent diabetes mellitus. Results of randomized crossover trial.
To determine whether therapy with exogenous insulin or sulfonylureas results in a postprandial pattern of carbohydrate metabolism… (More)
Is this relevant?
1986
1986
Effects of tolazamide and exogenous insulin on insulin action in patients with non-insulin-dependent diabetes mellitus.
To determine whether sulfonylureas and exogenous insulin have different effects on insulin action, we studied eight patients with… (More)
Is this relevant?
1985
1985
A case of chronic liver disease due to tolazamide.
Although chlorpropamide and tolbutamide are well recognized as causes of hepatotoxicity, there are only 3 reported cases of… (More)
Is this relevant?
1984
1984
Lichenoid drug reactions to chlorpropamide and tolazamide.
Many medications, including gold, antimalarials, quinidine, and thiazide diuretics have been implicated in lichenoid drug… (More)
Is this relevant?
1982
1982
Bioavailability of tolazamide from tablets: comparison of in vitro and in vivo results.
The relative bioavailability of tolazamide was determined, in healthy male volunteers, from four different tablet formulations… (More)
Is this relevant?
1980
1980
Impaired granulocyte adherence in mildly diabetic patients: effects of tolazamide treatment.
Granulocyte adherence in 10 of 15 untreated asymptomatic hyperglycemic diabetic outpatients (mean fasting glucose +/- SEM, 289… (More)
Is this relevant?
1978
1978
Tolazamide-induced hepatic dysfunction.
A case of tolazamide-induced hepatic injury is reported. Injury was documented by abnormal liver tests, including an elevated… (More)
Is this relevant?