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Tolazamide

Known as: N-(P-Toluenesulfonyl)-n'-hexamethyleniminourea, Tolazamidum, 1-(hexahydro-1-Azepinyl)-3-P-tolylsulfonylurea 
An intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. Tolazamide is converted into five major metabolites that are… 
National Institutes of Health

Related topics

Related topics

15 relations
Diabetes Mellitus, Non-Insulin-DependentIn BloodPregnancySulfonylurea Compounds

Broader (1)

Hypoglycemic Agents

Narrower (1)

Tolinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Detection of anti-diabetics in equine plasma and urine by liquid chromatography-tandem mass spectrometry.
Highly Cited
2002
Highly Cited
2002
Screening, library-assisted identification and validated quantification of oral antidiabetics of the sulfonylurea-type in plasma by atmospheric pressure chemical ionization liquid chromatography-mass…
Highly Cited
1996
Highly Cited
1996
Individual Sulfonylureas and Serious Hypoglycemia in Older People
OBJECTIVE: To compare the risk of serious hypoglycemia associated with the use of individual sulfonylureas in older people. 
Highly Cited
1992
Highly Cited
1992
Brand Loyalty, Entry, and Price Competition in Pharmaceuticals after the 1984 Drug Act
IN 1984, Congress enacted a new law that greatly affected the economics of the pharmaceutical industry in the United States. It… 
Highly Cited
1988
Highly Cited
1988
Characterization of the sulfonylurea receptor on beta cell membranes.
Highly Cited
1986
Highly Cited
1986
Effects of tolazamide and exogenous insulin on insulin action in patients with non-insulin-dependent diabetes mellitus.
To determine whether sulfonylureas and exogenous insulin have different effects on insulin action, we studied eight patients with… 
1984
1984
Nonenzymatic glucosylation of human serum albumin and its influence on binding capacity of sulfonylureas.
Review
1981
Review
1981
The pharmacology of sulfonylureas.
Highly Cited
1980
Highly Cited
1980
Nitrosation and mutagenicity of some amine drugs.
1956
1956
Ineffectiveness of Sulfonylureas in Alloxan Diabetic Rats.∗
Summary Oral administration of 100 mg 1-3-butyl-p-tolylsulfonylurea per kg body weight to normal rats results in a marked… 
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