Tissue Culture Infectious Dose 50%

Known as: 50 Percent Tissue Culture Infective Dose, {TCID50}, [TCID_50] 
A potency unit defined as a minimal dose of infectious material at which preparation causes cytopathic effects (changes in the morphology and… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
PURPOSE REOLYSIN (Oncolytics Biotech) consists of a wild-type oncolytic reovirus, which has selective cytotoxicity for tumor… (More)
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Highly Cited
2005
Highly Cited
2005
Three multiplex hemi-nested RT-PCR assays were developed to detect simultaneously 12 RNA respiratory viruses: influenza viruses A… (More)
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Highly Cited
2004
Highly Cited
2004
Poliovirus and enterovirus 71 (EV71) are both neurotropic enteroviruses that cause serious neurological diseases, such as… (More)
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Highly Cited
2003
Highly Cited
2003
The clinical presentation of infections caused by the heterogeneous group of the respiratory viruses can be very similar. Thus… (More)
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Highly Cited
2001
Highly Cited
2001
Calculation of titer estimates and use of titer reduction assays are fundamental approaches used by virologists. Titer assays… (More)
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Highly Cited
2000
Highly Cited
2000
The authors conducted a 2-year, multicenter, double-blind, placebo-controlled efficacy field trial of live, attenuated, cold… (More)
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Highly Cited
2000
Highly Cited
2000
A fluorogenic PCR-based method (TaqMan-PCR) was developed for typing and subtyping of influenza virus genomes in clinical… (More)
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Highly Cited
2000
Highly Cited
2000
We describe a multiplex reverse transcription-PCR (m-RT-PCR) assay that is able to detect and differentiate all known human… (More)
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Highly Cited
1986
Highly Cited
1986
In a study of Lassa fever in Sierra Leone, West Africa, we identified two variables associated with a high risk of death, and we… (More)
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Highly Cited
1981
Highly Cited
1981
To understand the transmission of respiratory syncytial virus, we examined the frequency of infection in volunteers after… (More)
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