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Thymidine Phosphorylase Inhibitor [EPC]
Known as:
Thymidine Phosphorylase Inhibitor
National Institutes of Health
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Thymidine Phosphorylase Inhibitors [MoA]
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
A phase I study of TAS-102 in combination with oxaliplatin (TAS-OX) for refractory metastatic colorectal cancer (mCRC).
M. Cecchini
,
J. Kortmansky
,
+7 authors
H. Hochster
Journal of Clinical Oncology
2019
Corpus ID: 86488360
630 Background: TAS-102 is an oral combination of the anti-metabolite 5-trifluorothymidine (FTD) and a thymidine phosphorylase…
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2012
2012
Abstract 1783: Trifluorothymidine incorporation into DNA strongly enforces the potential of TAS-102 and leads to remarkably prolonged survival of cancer patients
Nozomu Tanaka
,
Kei Oguchi
,
+5 authors
K. Noguchi
2012
Corpus ID: 75898696
TAS-102 is a novel oral antitumor agent, consisting of trifluorothymidine (FTD) as the active component and thymidine…
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2011
2011
Platelet derived endothelial cell growth factor/thymidine phosphorylase enhanced human IgE production.
Hideyuki Yamamoto
,
Takechiyo Yamada
,
+5 authors
S. Fujieda
Allergology International
2011
Corpus ID: 19151611
BACKGROUND Angiogenesis is one pathogenesis of allergic airway disease. METHODS A potent angiogenic factor is platelet-derived…
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2010
2010
Increased Migration by Stimulation of Thymidine Phosphorylase in Endothelial Cells of Different Origin
I. Bijnsdorp
,
Kim Vrijland
,
L. Vroling
,
M. Fukushima
,
G. Peters
Nucleosides, Nucleotides & Nucleic Acids
2010
Corpus ID: 7090766
Thymidine phosphorylase (TP) catalyzes the phosphorylytic cleavage of thymidine to thymine and deoxyribose-1-phosphate. The…
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2010
2010
The role of platelet-derived endothelial cell growth factor / thymidine phosphorylase in tumor behavior Nucleosides Nucleotides and Nucleic acids 27 : 681-91 , 2008
I. Bijnsdorp
,
M. D. Bruin
,
A. Laan
,
M. Fukushima
,
G. Peters
2010
Corpus ID: 261230239
2008
2008
Platelet Derived Endothelial Cell Growth Factor/Thymidine Phosphorylase Enhanced Human IgE Production
S. Fujieda
,
H. Yamamoto
2008
Corpus ID: 72730378
2005
2005
Low folate conditions may enhance the interaction of trifluorothymidine with antifolates in colon cancer cells
O. Temmink
,
Marco F. M. Hoogeland
,
M. Fukushima
,
G. Peters
Cancer Chemotherapy and Pharmacology
2005
Corpus ID: 13482266
Purpose: Trifluorothymidine (TFT) is a fluoropyrimidine that is part of the novel combination metabolite TAS-102, in which TFT is…
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