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Thromboxane Receptor

Known as: Thromboxane Receptors, TP Receptor, Thromboxanes Receptors 
Cell surface proteins that bind THROMBOXANES with high affinity and trigger intracellular changes influencing the behavior of cells. Some thromboxane… 
National Institutes of Health

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In BloodThromboxanesagonistsantagonists & inhibitors

Papers overview

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2011
2011
Novel HIV-1 Protease Inhibitors (PIs) Containing a Bicyclic P2 Functional Moiety, Tetrahydropyrano-Tetrahydrofuran, That Are Potent against Multi-PI-Resistant HIV-1 Variants
ABSTRACT We identified GRL-1388 and -1398, potent nonpeptidic human immunodeficiency virus type 1 (HIV-1) protease inhibitors… 
1993
1993
Resistance to cyclopentenylcytosine in murine leukemia L1210 cells.
Cyclopentenyl cytosine (CPEC) exhibits oncological activity in murine and human tumor cells and has now entered Phase I clinical… 
1990
1990
R68070, a combined thromboxane/endoperoxide receptor antagonist and thromboxane synthase inhibitor, inhibits human platelet activation in vitro and in vivo: a comparison with aspirin
We have investigated the effects of R68070 on platelet function in vitro and in vivo. The drug inhibits U46619induced aggregation… 
Review
1987
Review
1987
A pharmacological approach to thromboxane receptor antagonism.
Thromboxane A2 (TxA2) appears to be an important mediator of ischemia and hypoxia. Despite its short half-life and the fact that… 
1987
1987
Cardioprotective Actions of Specific Thromboxane Receptor Antagonist in Acute Myocardial Ischemia
Summary: Thromboxane A2 (TxA2) has been implicated as a potential mediator of myocardial damage during acute ischemia. A potent… 
1986
1986
Beneficial actions of thromboxane receptor antagonism in hemorrhagic shock.
The new specific thromboxane receptor antagonist, BM-13505, was infused intravenously (1 mg/kg bolus and 1 mg/kg hr continuous… 
Highly Cited
1986
Highly Cited
1986
Metabolic and functional consequences of introducing inositol 1,4,5-trisphosphate into saponin-permeabilized human platelets.
In an earlier study we reported the effect of inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] in releasing Ca2+ from highly purified… 
Highly Cited
1985
Highly Cited
1985
An Objective Assessment of the Interaction of Heparin and Its Fractions with Human Platelets
We have shown that heparin and heparin fractions cause in vitro platelet aggregation in a large portion of a normal population… 
Review
1970
Review
1970
Evaluation of a quantitative automated micro-hemagglutination assay for antibodies to Treponema pallidum.
In a survey of approximately 700 sera from clinically-defined donors, a quantitative automated microhemagglutination assay for… 
1968
1968
Homosexuality in female rats following testosterone implantation in the anterior hypothalamus.
Recently an experimental model of androgen-induced male homosexuality was produced. Castration of male rats within 24 hr of birth…