Thromboxane Production

Thromboxane Production consists of synthesis of widely distributed compounds formed by cyclooxygenase from polyunsaturated fatty acid prostaglandin… (More)
National Institutes of Health

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Review
2006
Review
2006
Aspirin resistance is the inability of aspirin to reduce platelet production of thromboxane A2 and thereby platelet activation… (More)
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Review
2003
Review
2003
Accelerated atherosclerosis and the increased risk of thrombotic vascular events in diabetes may result from dyslipidemia… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND We studied whether aspirin resistance, defined as failure of suppression of thromboxane generation, increases the risk… (More)
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Highly Cited
1995
Highly Cited
1995
The endothelium serves many functional roles, including the modulation of vascular smooth muscle tone through the release of… (More)
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1995
1995
Placentas obtained from women with preeclampsia produce more lipid peroxides and more thromboxane, but less prostacyclin, than… (More)
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Highly Cited
1991
Highly Cited
1991
Erythrocytes promoted platelet reactivity in a plasma medium, as demonstrated in an in vitro system that independently evaluated… (More)
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Highly Cited
1987
Highly Cited
1987
The capacity of platelets to generate thromboxane A2, reflected by measurement of serum thromboxane B2 (TxB2), greatly exceeds… (More)
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Highly Cited
1985
Highly Cited
1985
Preeclampsia is characterized by increased vasoconstriction frequently associated with increased platelet aggregation, reduced… (More)
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Highly Cited
1985
Highly Cited
1985
Preincubation of rabbit platelet-rich plasma with cocaine hydrochloride, at low and high concentrations, increased the platelet… (More)
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Highly Cited
1982
Highly Cited
1982
Acetylation of platelet cyclooxygenase by oral aspirin is dose dependent and cumulative with repeated administration. However, no… (More)
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