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Thrombocytosis
Known as:
Thrombocythemia
, THROMBOCYTHAEMIA
, Thrombocytosis [Disease/Finding]
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A hematology test result that indicates the presence of higher than normal platelet counts in the peripheral blood.
National Institutes of Health
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Related topics
Related topics
48 relations
Acute Myeloid Leukemia Arising from Previous Myelodysplastic Syndrome
Acute Myeloid Leukemia with Myelodysplasia-Related Changes
Acute myeloid leukemia with multilineage dysplasia
Blood Platelets
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Broader (2)
Blood Platelet Disorders
Hematological Disease
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Somatic mutations of calreticulin in myeloproliferative neoplasms.
T. Klampfl
,
H. Gisslinger
,
+26 authors
R. Kralovics
New England Journal of Medicine
2013
Corpus ID: 14787432
BACKGROUND Approximately 50 to 60% of patients with essential thrombocythemia or primary myelofibrosis carry a mutation in the…
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Highly Cited
2013
Highly Cited
2013
Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2.
J. Nangalia
,
C. Massie
,
+49 authors
A. Green
New England Journal of Medicine
2013
Corpus ID: 11205725
BACKGROUND Somatic mutations in the Janus kinase 2 gene (JAK2) occur in many myeloproliferative neoplasms, but the molecular…
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Highly Cited
2012
Highly Cited
2012
Paraneoplastic thrombocytosis in ovarian cancer.
R. Stone
,
A. Nick
,
+31 authors
A. Sood
New England Journal of Medicine
2012
Corpus ID: 2629731
BACKGROUND The mechanisms of paraneoplastic thrombocytosis in ovarian cancer and the role that platelets play in abetting cancer…
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Review
2008
Review
2008
Classification and diagnosis of myeloproliferative neoplasms: The 2008 World Health Organization criteria and point-of-care diagnostic algorithms
A. Tefferi
,
J. Vardiman
Leukemia
2008
Corpus ID: 25649229
The 2001 World Health Organization (WHO) treatise on the classification of hematopoietic tumors lists chronic myeloproliferative…
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Highly Cited
2007
Highly Cited
2007
JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis.
L. Scott
,
W. Tong
,
+14 authors
Anthony R. Green
New England Journal of Medicine
2007
Corpus ID: 20065263
BACKGROUND The V617F mutation, which causes the substitution of phenylalanine for valine at position 617 of the Janus kinase (JAK…
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Highly Cited
2006
Highly Cited
2006
MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients.
A. Pardanani
,
Ross L. Levine
,
+11 authors
A. Tefferi
Blood
2006
Corpus ID: 17388936
Recently, a gain-of-function MPL mutation, MPLW515L, was described in patients with JAK2V617F-negative myelofibrosis with myeloid…
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Highly Cited
2005
Highly Cited
2005
A gain-of-function mutation of JAK2 in myeloproliferative disorders.
R. Kralovics
,
F. Passamonti
,
+6 authors
R. Skoda
New England Journal of Medicine
2005
Corpus ID: 17583146
BACKGROUND Polycythemia vera, essential thrombocythemia, and idiopathic myelofibrosis are clonal myeloproliferative disorders…
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Highly Cited
2005
Highly Cited
2005
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
R. Levine
,
M. Wadleigh
,
+26 authors
D. Gilliland
Cancer Cell
2005
Corpus ID: 45000024
Highly Cited
2005
Highly Cited
2005
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
C. James
,
V. Ugo
,
+11 authors
W. Vainchenker
Nature
2005
Corpus ID: 4399974
Myeloproliferative disorders are clonal haematopoietic stem cell malignancies characterized by independency or hypersensitivity…
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Highly Cited
2001
Highly Cited
2001
Interleukin-6 stimulates thrombopoiesis through thrombopoietin: role in inflammatory thrombocytosis.
A. Kaser
,
G. Brandacher
,
+13 authors
H. Tilg
Blood
2001
Corpus ID: 5125912
Baseline platelet production is dependent on thrombopoietin (TPO). TPO is constitutively produced and primarily regulated by…
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