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Thiosemicarbazones, direct acting antivirals

Known as: Thiosemicarbazones 
National Institutes of Health

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Thiosemicarbazones

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Highly Cited
2012
Highly Cited
2012
DNA binding, antioxidant, cytotoxicity (MTT, lactate dehydrogenase, NO), and cellular uptake studies of structurally different nickel(II) thiosemicarbazone complexes: synthesis, spectroscopy…
Three new nickel(II) thiosemicarbazone complexes have been synthesized and characterized by analytical, spectral, and single… 
Highly Cited
2009
Highly Cited
2009
Platinum-based complexes of bioactive 3-(5-nitrofuryl)acroleine thiosemicarbazones showing anti-Trypanosoma cruzi activity.
2009
2009
Synthesis, structural characterization, and biological evaluation of oxorhenium(V) complexes with a novel type of thiosemicarbazones derived from N-[N',N'-dialkylamino(thiocarbonyl)]benzimidoyl…
Reactions of N-[N',N'-diethylamino(thiocarbonyl)]benzimidoyl chloride with 4,4-dialkylthiosemicarbazides give a novel class of… 
2008
2008
Synthesis and ribonucleotide reductase inhibitory activity of thiosemicarbazones.
Highly Cited
2007
Highly Cited
2007
Spectral and structural studies of mono- and binuclear copper(II) complexes of salicylaldehyde N(4)-substituted thiosemicarbazones
Highly Cited
2005
Highly Cited
2005
Novel bidentate complexes of Cu(II) derived from 5-nitrofuran-2-carboxaldehyde thiosemicarbazones with antiamoebic activity against E. histolytica.
2001
2001
Synthesis, characterisation and antiamoebic activity of new thiophene-2-carboxaldehyde thiosemicarbazone derivatives and their cyclooctadiene Ru(II) complexes.
1999
1999
Multiple mechanisms for cytotoxicity induced by copper(II) complexes of 2‐acetylpyrazine‐N‐substituted thiosemicarbazones
The purpose of this study was to evaluate the mechanism by which 2-acetylpyrazine-4N-substituted thiosemicarbazone copper II… 
Highly Cited
1977
Highly Cited
1977
Elucidation of the structure of the antineoplastic agents, 2-formylpyridine and 1-formylisoquinoline thiosemicarbazones.
The geometrical isomers of the antineoplastic agents 2-formylpyridine and 1-formylisoquinoline thiosemicarbazones were… 
Highly Cited
1973
Highly Cited
1973
Inhibition of RNA-dependent DNA polymerase of Rous sarcoma virus by thiosemicarbazones and several cations.
The RNA-dependent DNA polymerase of Rous sarcoma virus is inhibited by N-methyl isatin beta-thiosemicarbazone and by… 
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