Thioredoxin Reductase (NADPH)

Known as: NADP Thioredoxin Reductase, Thioredoxin Reductase, Reductase, NADP-Thioredoxin 
A FLAVOPROTEIN enzyme that catalyzes the oxidation of THIOREDOXINS to thioredoxin disulfide in the presence of NADP+. It was formerly listed as EC 1… (More)
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Thioredoxin (Trx) and thioredoxin reductase (TrxR) plus NADPH, comprising the thioredoxin system, has a large number of functions… (More)
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Highly Cited
2007
Highly Cited
2007
Arsenic trioxide (ATO) is an effective cancer therapeutic drug for acute promyelocytic leukemia and has potential anticancer… (More)
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Highly Cited
2004
Highly Cited
2004
Oxygen radicals regulate many physiological processes, such as signaling, proliferation, and apoptosis, and thus play a pivotal… (More)
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Highly Cited
2004
Highly Cited
2004
Plants contain three thioredoxin systems. Chloroplast thioredoxins are reduced by ferredoxin-thioredoxin reductase, whereas the… (More)
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Review
2001
Review
2001
The mammalian thioredoxins are a family of small (approximately 12 kDa) redox proteins that undergo NADPH-dependent reduction by… (More)
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Review
2000
Review
2000
Thioredoxin, thioredoxin reductase and NADPH, the thioredoxin system, is ubiquitous from Archea to man. Thioredoxins, with a… (More)
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Review
2000
Review
2000
Thioredoxin reductase (EC 1.6.4.5) is a widely distributed flavoprotein that catalyzes the NADPH-dependent reduction of… (More)
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Review
1999
Review
1999
Numerous studies in animal models and more recent studies in humans have demonstrated cancer chemopreventive effects with Se… (More)
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Highly Cited
1994
Highly Cited
1994
A 25-kDa antioxidant enzyme that provides protection against oxidation systems capable of generating reactive oxygen and sulfur… (More)
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Highly Cited
1982
Highly Cited
1982
A reproducible scheme has been developed for the preparation of rat liver thioredoxin and thioredoxin reductase (EC 1.6.4.5) by… (More)
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