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Thioacetazone

Known as: Thioparamizone, Thioacetazon, Amithiozone 
A thiosemicarbazone prodrug with antitubercular activity. Although the exact mechanism by which thioacetazone exerts its effect has yet to be fully… 
National Institutes of Health

Related topics

Related topics

15 relations

Broader (1)

Antitubercular Agents

Narrower (7)

ContebenKBF 611ParazoneSRI 224
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis.
Highly Cited
2002
Highly Cited
2002
The Antituberculosis Drug Ethionamide Is Activated by a Flavoprotein Monooxygenase*
Ethionamide (ETA), a prodrug that must undergo metabolic activation to exert its cytotoxic effects, is a second line drug against… 
Highly Cited
2000
Highly Cited
2000
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis.
Ethionamide (ETA) is an important component of second-line therapy for the treatment of multidrug-resistant tuberculosis… 
Review
1999
Review
1999
Studies on the treatment of tuberculosis undertaken by the British Medical Research Council Tuberculosis Units, 1946-1986, with relevant subsequent publications.
This review describes the studies on the treatment of tuberculosis carried out by the British Medical Research Council's… 
Highly Cited
1994
Highly Cited
1994
The new tuberculosis.
Despite the fact that there are 8 million new cases of tuberculosis (TB) annually and 3 million deaths, TB has been a neglected… 
Review
1992
Review
1992
Proposed minimal standards for the genus Mycobacterium and for description of new slowly growing Mycobacterium species.
In accordance with Recommendation 30b of the International Code of Nomenclature of Bacteria, which calls for the development of… 
Highly Cited
1991
Highly Cited
1991
Toxic hepatitis with isoniazid and rifampin. A meta-analysis.
ALT = serum alanine aminotransferase; AST serum aspartate aminotransferase; BIU bilirubin; EMB ethambutol; INH isoniazid; NSM not… 
Highly Cited
1991
Highly Cited
1991
Increased mortality and tuberculosis treatment failure rate among human immunodeficiency virus (HIV) seropositive compared with HIV seronegative patients with pulmonary tuberculosis treated with…
To evaluate their treatment outcomes 170 human immunodeficiency virus (HIV) seropositive and 597 HIV seronegative patients with… 
Highly Cited
1991
Highly Cited
1991
Cutaneous hypersensitivity reactions due to thiacetazone in HIV-1 seropositive patients treated for tuberculosis
Review
1990
Review
1990
Tuberculosis and human immunodeficiency virus infection in developing countries
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