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Thiazolidinedione Antidiabetic Agent

Any antidiabetic agent with the glitazone (thiazolidinedione) base structure with antihyperglycemic activity. Glitazone antidiabetic agents… Expand
National Institutes of Health

Papers overview

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2015
2015
There is an exponential increase in the incidence of diabetes the world over, more so in the Indian subcontinent1. Recent… Expand
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2013
2013
Pioglitazone (PGZ), a thiazolidinedione antidiabetic agent, is reported as a potent and selective activator of peroxisome… Expand
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2005
2005
Troglitazone (TRO), an effective thiazolidinedione antidiabetic agent, was reported to produce idiosyncratic hepatotoxic effects… Expand
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2005
2005
Troglitazone is a thiazolidinedione antidiabetic agent with insulin-sensitizing activities that was withdrawn from the market in… Expand
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Highly Cited
2002
Highly Cited
2002
Carcinogenic potential of the thiazolidinedione antidiabetic troglitazone was assessed in 104-week studies in mice and rats. Mice… Expand
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2002
2002
The antidiabetic agent troglitazone was given to groups of 4 cynomolgus monkeys per sex at 300, 600, or 1200 mg/kg daily by… Expand
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Highly Cited
2001
Highly Cited
2001
CONTEXT Soon after initial marketing in March 1997, troglitazone, the first thiazolidinedione antidiabetic agent, was found to… Expand
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2001
2001
  • J. Lefkowitch
  • Current opinion in gastroenterology
  • 2001
  • Corpus ID: 12281320
Immunohistochemistry provided new perspectives on diagnostic problems in liver pathology in 1993, including the use of a… Expand
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1996
1996
1. The fate of [14C]BRL 49653C, a novel thiazolidinedione antidiabetic agent, has been studied following oral administration to… Expand
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Highly Cited
1994
Highly Cited
1994
The effects of a thiazolidinedione antidiabetic agent (CS‐045) on diabetic metabolic abnormalities were studied in a double‐blind… Expand
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