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Thiazide Diuretics

Known as: diuretic thiazides, [CV701] THIAZIDES/RELATED DIURETICS, Thiazide Diuretic 
Any benzothiadiazide derivative or other thiazide-like agent with diuretic and anti-hypertensive activity. Thiazide diuretics inhibit the sodium… Expand
National Institutes of Health

Related topics

Related topics

6 relations

Broader (1)

Antihypertensive Agents

Narrower (3)

Chlorothiazide 500 MG InjectionChlorthalidone 25 MG Oral TabletMetolazone 5 MG Oral Tablet
EthiazideThiazides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Mechanisms for blood pressure lowering and metabolic effects of thiazide and thiazide-like diuretics
Thiazide and thiazide-like diuretics are among the most commonly used antihypertensives and have been available for over 50 years… Expand
Highly Cited
2008
Highly Cited
2008
Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients.
BACKGROUND The optimal combination drug therapy for hypertension is not established, although current U.S. guidelines recommend… Expand
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Highly Cited
2008
Highly Cited
2008
Activation of the thiazide-sensitive Na+-Cl– cotransporter by the WNK-regulated kinases SPAK and OSR1
Mutations increasing WNK1 kinase expression in humans cause the pseudohypoaldosteronism type II hypertension syndrome. This… Expand
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Highly Cited
2005
Highly Cited
2005
Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia.
Thiazide diuretics enhance renal Na+ excretion by blocking the Na+-Cl- cotransporter (NCC), and mutations in NCC result in… Expand
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Highly Cited
2003
Highly Cited
2003
Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure.
The National High Blood Pressure Education Program presents the complete Seventh Report of the Joint National Committee on… Expand
Highly Cited
2003
Highly Cited
2003
2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension
Objective Hypertension is estimated to cause 4.5% of current global disease burden and is as prevalent in many developing… Expand
Highly Cited
2000
Highly Cited
2000
Hypertension and antihypertensive therapy as risk factors for type 2 diabetes mellitus. Atherosclerosis Risk in Communities Study.
BACKGROUND Previous research has suggested that thiazide diuretics and beta-blockers may promote the development of type 2… Expand
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Highly Cited
2000
Highly Cited
2000
Hypokalemia associated with diuretic use and cardiovascular events in the Systolic Hypertension in the Elderly Program.
The treatment of hypertension with high-dose thiazide diuretics results in potassium depletion and a limited benefit for… Expand
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Highly Cited
1995
Highly Cited
1995
Medication use and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis
Background Toxic epidermal necrolysis and Stevens–Johnson syndrome are rare, life-threatening, drug-induced cutaneous reactions… Expand
Highly Cited
1981
Highly Cited
1981
Effects of thiazide diuretics on plasma lipids and lipoproteins in mildly hypertensive patients: a double-blind controlled trial.
A blood lipid-lipoprotein elevating effect of the diuretics hydrochlorothiazide and chlorthalidone in mildly hypertensive men has… Expand
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