Therapy-Related Leukemia

Known as: Therapy Related Leukemia, Treatment Induced Leukemia, Treatment Related Leukemia 
A leukemia arising as a result of the mutagenic effect of chemotherapy agents that are used for the treatment of a malignant tumor or exposure to… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2018
051019792018

Papers overview

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Highly Cited
2012
Highly Cited
2012
Topoisomerase poisons such as the epipodophyllotoxin etoposide are widely used effective cytotoxic anticancer agents. However… (More)
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Highly Cited
2007
Highly Cited
2007
Therapy-related myelodysplastic syndrome/acute myeloid leukemia (t-MDS/AML) is an increasingly recognized treatment complication… (More)
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Highly Cited
2000
Highly Cited
2000
We analyzed data on 612 patients who had undergone high-dose chemoradiotherapy (HDT) with autologous stem cell rescue for Hodgkin… (More)
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2000
2000
Therapy-related leukemia associated with chemotherapy, particularly alkylating agents and topoisomerase II inhibitors, are being… (More)
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Highly Cited
2000
Highly Cited
2000
Several genetic polymorphisms in metabolic activation or detoxification enzymes have been associated with susceptibility to… (More)
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Highly Cited
1999
Highly Cited
1999
MLL (ALL1, Htrx, HRX), which is located on chromosome band 11q23, frequently is rearranged in patients with therapy-related acute… (More)
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1999
1999
Combination chemotherapy and radiation therapy have contributed to the successful treatment of various cancer patients. But the… (More)
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Highly Cited
1996
Highly Cited
1996
During the last decade the frequency of therapy-related acute leukemia (t-leuk) and myelodysplastic syndrome (t-MDS) has been… (More)
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1996
1996
We investigated the frequency of p53 mutations in 19 pediatric cases of therapy-related leukemia or myelodysplastic syndrome… (More)
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1979
1979
Fifteen patients developed acute nonlymphocytic leukemia (ANLL) 31 to 182 months following chemotherapy and/or radiotherapy for… (More)
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