Tetracyclines

Known as: Tetracyclines [Chemical/Ingredient] 
Closely congeneric derivatives of the polycyclic naphthacenecarboxamide. (Gilman et al., Goodman and Gilman's The Pharmacological Basis of… (More)

Topic mentions per year

Topic mentions per year

1954-2017
051019542016

Papers overview

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2015
2015
In recent years, tetracyclines, such as doxycycline, have become broadly used to control gene expression by virtue of the Tet-on… (More)
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2009
2009
In addition to their bacteriostatic effect, tetracyclines, which are often used in the treatment of periodontitis, also present… (More)
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Highly Cited
2006
Highly Cited
2006
Tetracyclines are effective but slow-acting antimalarial drugs whose mechanism of action remains uncertain. To characterize the… (More)
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2001
2001
Cerebral deposition of beta-amyloid is a major neuropathological feature in Alzheimer's disease. Here we show that tetracyclines… (More)
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2000
2000
Chemically modified tetracyclines (CMTs) are thought to inhibit bone resorption through inhibition of matrix metalloproteinases… (More)
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1999
1999
Tetracyclines (doxycycline and minocycline) inhibit inducible NO synthase expression and augment cyclooxygenase (COX)-2… (More)
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Highly Cited
1998
Highly Cited
1998
Ischemic stroke is the most common life-threatening neurological disease and has limited therapeutic options. One component of… (More)
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1997
1997
Chemically modified tetracyclines [CMT-3 (IC50 approximately 6-13 microM = approximately 2.5-5 microg/ml) and CMT-8 (IC50… (More)
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Highly Cited
1996
Highly Cited
1996
Tetracyclines have recently been shown to have "chondroprotective" effects in inflammatory arthritides in animal models. Since… (More)
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1987
1987
Tetracyclines (including the semi-synthetic analogues, minocycline and doxycycline) are considered useful adjuncts in periodontal… (More)
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