FAQ

Tetrachlorodibenzodioxin

Known as: TCDD, PCDD 48, Dioxin 
2,3,7,8-Tetrachlorodibenzo-p-dioxin which is often referred to simply as dioxin and is the reference for a number of compounds which are similar… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1956-2017
010020019562016

Related topics

Related topics

10 relations
2,3,7,8-tetrafluorodibenzodioxin2,8-dichlorodibenzo-4-dioxinCarcinogensNK 252
(More)

Broader (3)

DioxaneDioxinsPolychlorinated Dibenzodioxins

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Tetrachlorodibenzodioxin
Carcinogens
Dioxins
Dioxane
Polychlorinated Dibenzodioxins
2,8-dichlorodibenzo-4-dioxin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor.
Activation of the aryl hydrocarbon receptor (AHR) by environmental xenobiotic toxic chemicals, for instance 2,3,7,8… (More)
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Highly Cited
2007
Highly Cited
2007
Dioxin receptor is a ligand-dependent E3 ubiquitin ligase.
Fat-soluble ligands, including sex steroid hormones and environmental toxins, activate ligand-dependent DNA-sequence-specific… (More)
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Highly Cited
2000
Highly Cited
2000
Paternal concentrations of dioxin and sex ratio of offspring.
BACKGROUND 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD or dioxin), is commonly considered the most toxic man-made substance. We… (More)
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Highly Cited
1997
Highly Cited
1997
Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor.
BACKGROUND The aryl hydrocarbon receptor (AhR or dioxin receptor) is a ligand-activated transcription factor that is considered… (More)
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Highly Cited
1996
Highly Cited
1996
Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity.
Acute exposure of mammals to the environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) results in a diverse set of… (More)
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Highly Cited
1994
Highly Cited
1994
Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2.
Previously, levels of a novel human mRNA, detected by a recombinant cDNA designated clone 1, were shown to be increased 50-fold… (More)
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Highly Cited
1993
Highly Cited
1993
Endometriosis in rhesus monkeys (Macaca mulatta) following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
The incidence of the reproductive disease endometriosis was determined in a colony of rhesus monkeys chronically exposed to 2,3,7… (More)
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Highly Cited
1992
Highly Cited
1992
Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor.
The Ah (dioxin) receptor binds a number of widely disseminated environmental pollutants, including 2,3,7,8-tetrachlorodibenzo-p… (More)
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Highly Cited
1991
Highly Cited
1991
Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Indole-3-carbinol (I3C) is a secondary plant metabolite produced in vegetables of the Brassica genus, including cabbage… (More)
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Highly Cited
1976
Highly Cited
1976
Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase.
We previously hypothesized that the genetic trait of aromatic hydrocarbon nonresponsiveness (the failure in certain inbred… (More)
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