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Tetrachlorodibenzodioxin

Known as: TCDD, PCDD 48, Dioxin 
2,3,7,8-Tetrachlorodibenzo-p-dioxin which is often referred to simply as dioxin and is the reference for a number of compounds which are similar… Expand
National Institutes of Health

Related topics

Related topics

16 relations
2,3,7,8-tetrafluorodibenzodioxin2,8-dichlorodibenzo-4-dioxinCarcinogensDioxin:MCnc:Pt:Air:Qn
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Broader (5)

DioxaneDioxinsHeterocyclic Compounds, 1-RingPolychlorinated Dibenzodioxins
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
Activation of the aryl hydrocarbon receptor (AHR) by environmental xenobiotic toxic chemicals, for instance 2,3,7,8… Expand
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Highly Cited
2010
Highly Cited
2010
Science and decisions: advancing risk assessment.
At the request of the U.S. Environmental Protection Agency (EPA), the National Research Council (NRC) recently completed a major… Expand
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Highly Cited
2008
Highly Cited
2008
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor best known for mediating the toxicity of dioxin… Expand
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Review
2003
Review
2003
Functional role of AhR in the expression of toxic effects by TCDD.
Cytochrome P450 1A1 (CYP1A1) is one of the xenobiotic metabolizing enzymes (XMEs), which is induced by polycyclic aromatic… Expand
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Review
1999
Review
1999
Induction of cytochrome P4501A1.
Cytochrome P4501A1 is a substrate-inducible microsomal enzyme that oxygenates polycyclic aromatic hydrocarbons, such as the… Expand
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Review
1997
Review
1997
Steroid receptor interactions with heat shock protein and immunophilin chaperones.
We have provided a historical perspective on a body of steroid receptor research dealing with the structure and physiological… Expand
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Highly Cited
1996
Highly Cited
1996
Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development.
The Ah receptor (AHR) is a ligand-activated transcription factor that mediates a pleiotropic response to environmental… Expand
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Highly Cited
1996
Highly Cited
1996
Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity.
Acute exposure of mammals to the environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) results in a diverse set of… Expand
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Highly Cited
1996
Highly Cited
1996
Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.
A human cytochrome P-450 (P450) 1B1 cDNA was expressed in Saccharomyces cerevisiae and the microsomes containing P450 1B1 were… Expand
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Review
1990
Review
1990
Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic…
  • Stephen Safe
  • Critical reviews in toxicology
  • 1990
    • Corpus ID: 27477203
Halogenated aromatic compounds, typified by the polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), biphenyls (PCBs… Expand
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