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Tetrachlorodibenzodioxin

Known as: TCDD, PCDD 48, Dioxin 
2,3,7,8-Tetrachlorodibenzo-p-dioxin which is often referred to simply as dioxin and is the reference for a number of compounds which are similar… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Activation of the aryl hydrocarbon receptor (AHR) by environmental xenobiotic toxic chemicals, for instance 2,3,7,8… Expand
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Highly Cited
2010
Highly Cited
2010
At the request of the U.S. Environmental Protection Agency (EPA), the National Research Council (NRC) recently completed a major… Expand
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Highly Cited
2008
Highly Cited
2008
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor best known for mediating the toxicity of dioxin… Expand
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Review
2003
Review
2003
Cytochrome P450 1A1 (CYP1A1) is one of the xenobiotic metabolizing enzymes (XMEs), which is induced by polycyclic aromatic… Expand
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Review
1999
Review
1999
Cytochrome P4501A1 is a substrate-inducible microsomal enzyme that oxygenates polycyclic aromatic hydrocarbons, such as the… Expand
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Review
1997
Review
1997
We have provided a historical perspective on a body of steroid receptor research dealing with the structure and physiological… Expand
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Highly Cited
1996
Highly Cited
1996
The Ah receptor (AHR) is a ligand-activated transcription factor that mediates a pleiotropic response to environmental… Expand
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Highly Cited
1996
Highly Cited
1996
Acute exposure of mammals to the environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) results in a diverse set of… Expand
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Highly Cited
1996
Highly Cited
1996
A human cytochrome P-450 (P450) 1B1 cDNA was expressed in Saccharomyces cerevisiae and the microsomes containing P450 1B1 were… Expand
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Review
1990
Review
1990
  • Stephen Safe
  • Critical reviews in toxicology
  • 1990
  • Corpus ID: 27477203
Halogenated aromatic compounds, typified by the polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), biphenyls (PCBs… Expand
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