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Temocapril

Known as: (2S-(2alpha,6beta(R*)))-6-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)tetrahydro-5-oxo-2-(2-thienyl)-1,4-thiazepine-4(5H)-acetic Acid, Temocaprilum 
 
National Institutes of Health

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Related topics

1 relation
temocapril hydrochloride

Papers overview

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Highly Cited
2006
Highly Cited
2006
Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril
Recent reports have shown that genetic polymorphisms in organic anion transporting polypeptide (OATP) 1B1 have an effect on the… Expand
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Highly Cited
2006
Highly Cited
2006
Aldosterone breakthrough during therapy with angiotensin‐converting enzyme inhibitors and angiotensin II receptor blockers in proteinuric patients with immunoglobulin A nephropathy
Background:  We are investigating whether aldosterone breakthrough negatively impacts on the antiproteinuric effects of… Expand
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Highly Cited
2005
Highly Cited
2005
Temporary angiotensin II blockade at the prediabetic stage attenuates the development of renal injury in type 2 diabetic rats.
Whether temporary angiotensin II (AngII) blockade at the prediabetic stage attenuates renal injury in type 2 diabetic OLETF rats… Expand
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Highly Cited
2004
Highly Cited
2004
Blockade of the renin–angiotensin system decreases adipocyte size with improvement in insulin sensitivity
Objective Based on results of in vitro studies, it has been hypothesized that blockade of the renin–angiotensin system (RAS… Expand
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Highly Cited
2003
Highly Cited
2003
Blockade of the Renin-Angiotensin System Increases Adiponectin Concentrations in Patients With Essential Hypertension
Abstract—Adiponectin, an adipocyte-derived protein, has been suggested to play an important role in insulin sensitivity. We… Expand
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Highly Cited
2002
Highly Cited
2002
ACE Inhibitor Improves Insulin Resistance in Diabetic Mouse Via Bradykinin and NO
Improvement of insulin resistance by ACE inhibitors has been suggested; however, this mechanism has not been proved. We… Expand
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2002
2002
Differential effects of a long-acting angiotensin converting enzyme inhibitor (temocapril) and a long-acting calcium antagonist (amlodipine) on ventricular ectopic beats in older hypertensive…
We studied differences in the effects of a long-acting angiotensin-converting enzyme (ACE) inhibitor (temocapril) and a long… Expand
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Highly Cited
2000
Highly Cited
2000
Potential contribution of a novel antifibrotic factor, hepatocyte growth factor, to prevention of myocardial fibrosis by angiotensin II blockade in cardiomyopathic hamsters.
BACKGROUND Because hepatocyte growth factor (HGF) prevented and/or regressed fibrosis in liver and pulmonary injury models, HGF… Expand
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Highly Cited
1997
Highly Cited
1997
Chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade: effects on cardiovascular remodeling in rats induced by the long-term blockade of nitric oxide synthesis.
We have shown previously that angiotensin-converting enzyme (ACE) inhibitors prevent coronary vascular remodeling (medial… Expand
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Highly Cited
1997
Highly Cited
1997
Converting enzyme inhibitor improves forearm reactive hyperemia in essential hypertension.
Endothelial function is known to be impaired in essential hypertensive patients. In this study, we examined whether… Expand
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