Telomerase RNA Component

Known as: hTERC, telomerase RNA component (Terc), TERC 
Telomerase RNA component is the ribonucleic acid subunit of telomerase. Telomerase uses the species-specific RNA sequences as the templates to… (More)
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
Telomerase is a multisubunit ribonucleoprotein (RNP) complex that adds telomere repeats to the ends of chromosomes. Three… (More)
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Highly Cited
2008
Highly Cited
2008
Dyskeratosis congenita is a premature aging syndrome characterized by muco-cutaneous features and a range of other abnormalities… (More)
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Highly Cited
2007
Highly Cited
2007
Idiopathic pulmonary fibrosis (IPF) is an adult-onset, lethal, scarring lung disease of unknown etiology. Some individuals with… (More)
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Highly Cited
2007
Highly Cited
2007
Dyskeratosis congenita (DC) is characterized by multiple features including mucocutaneous abnormalities, bone marrow failure and… (More)
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Review
2004
Review
2004
Telomeres are essential for genome stability in all eukaryotes. Changes in telomere functions and the associated chromosomal… (More)
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Highly Cited
2003
Highly Cited
2003
Aplastic anaemia in adults is usually acquired, but rarely constitutional types of bone marrow failure can occur late in life. We… (More)
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Highly Cited
2003
Highly Cited
2003
Mutations in the human telomerase RNA (TERC) occur in autosomal dominant dyskeratosis congenita (DKC). Because of the possibility… (More)
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Highly Cited
2001
Highly Cited
2001
Telomerase is a reverse transcriptase that adds telomeric repeats to chromosomal ends. In most normal human somatic cells… (More)
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Highly Cited
1999
Highly Cited
1999
Telomere length is maintained by the de novo addition of telomere repeats by telomerase, yet recombination can elongate telomeres… (More)
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Highly Cited
1998
Highly Cited
1998
The ribonucleoprotein enzyme telomerase synthesizes telomeric DNA onto chromosome ends. Telomere length is maintained, by the… (More)
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