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Telapristone

Known as: 11Beta-(4-(dimethylamino)phenyl)-17-hydroxy-21-methoxy-19- norpregna-4,9-diene-3,20-dione 
An orally available 21-substituted-19-nor-progestin and selective progesterone receptor modulator (SPRM), with potential anti-progesterone and… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Selective progesterone receptor modulators (SPRMs) are new class of compounds developed to target the progesterone receptor with… Expand
Review
2018
Review
2018
Purpose of ReviewReview of the latest advances in the treatment of uterine fibroids. Addressing conservative management, medical… Expand
2017
2017
Background: Telapristone (CDB-4124 or Proellex®) is a PRM (progesterone antagonist) under development for treatment of uterine… Expand
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Review
2013
Review
2013
Uterine leiomyomata are benign, monoclonal tumors arising from smooth muscle cells, which belong to one of the most common… Expand
Review
2012
Review
2012
The majority of symptomatic uterine fibroids are currently treated by surgical interventions (myomectomy or hysterectomy) or… Expand
2011
2011
Telapristone is a selective progesterone antagonist that is being developed for the long-term treatment of symptoms associated… Expand
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2011
2011
Objective: Selective progesterone receptor modulators (SPRMs), such as asoprisnil (J867) and ulipristal (CDB-2914), have been… Expand
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