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Telapristone

Known as: 11Beta-(4-(dimethylamino)phenyl)-17-hydroxy-21-methoxy-19- norpregna-4,9-diene-3,20-dione 
An orally available 21-substituted-19-nor-progestin and selective progesterone receptor modulator (SPRM), with potential anti-progesterone and… Expand
National Institutes of Health

Papers overview

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2020
2020
Selective progesterone receptor modulators (SPRMs) are new class of compounds developed to target the progesterone receptor with… Expand
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Review
2018
Review
2018
Purpose of ReviewReview of the latest advances in the treatment of uterine fibroids. Addressing conservative management, medical… Expand
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2017
2017
Background: Telapristone (CDB-4124 or Proellex®) is a PRM (progesterone antagonist) under development for treatment of uterine… Expand
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Review
2013
Review
2013
Uterine leiomyomata are benign, monoclonal tumors arising from smooth muscle cells, which belong to one of the most common… Expand
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Review
2012
Review
2012
The majority of symptomatic uterine fibroids are currently treated by surgical interventions (myomectomy or hysterectomy) or… Expand
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2011
2011
Telapristone is a selective progesterone antagonist that is being developed for the long-term treatment of symptoms associated… Expand
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2011
2011
Objective: Selective progesterone receptor modulators (SPRMs), such as asoprisnil (J867) and ulipristal (CDB-2914), have been… Expand
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