Tay-Sachs Disease

Known as: Hexosaminidase A deficiency, Gangliosidosis GM2, Type I, GANGLIOSIDOSIS GM2 TYPE 1 
An autosomal recessive neurodegenerative disorder characterized by the onset in infancy of an exaggerated startle response, followed by paralysis… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
© The Ecological Society of America www.frontiersinecology.org T Millennium Ecosystem Assessment (MA) advanced a powerful vision… (More)
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2003
2003
Tay-Sachs Disease (TSD) is an autosomal recessive neurodegenerative disorder. TSD is prevalent in the Ashkenazi Jewish population… (More)
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Highly Cited
2001
Highly Cited
2001
Nathaniel Kleitman was the first to observe that sleep deprivation in humans did not eliminate the ability to perform… (More)
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Highly Cited
2000
Highly Cited
2000
Since 1970, more than 1.4 million individuals worldwide have been screened voluntarily to determine if they are carriers of the… (More)
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Highly Cited
1999
Highly Cited
1999
We consider the execution of portfolio transactions with the aim of minimizing a combination of volatility risk and transaction… (More)
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Highly Cited
1998
Highly Cited
1998
Various theories have been proposed to explain momentum in stock returns. We test the gradual-information-diffusion model of Hong… (More)
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Highly Cited
1996
Highly Cited
1996
Programs for education, screening, and counseling of senior-high-school students, in populations at high risk for Tay-Sachs and… (More)
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Highly Cited
1996
Highly Cited
1996
We have generated mouse models of human Tay-Sachs and Sandhoff diseases by targeted disruption of the Hexa (alpha subunit) or… (More)
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1979
1979
Enzyme replacement therapy was attempted with two Tay-Sachs-diseased individuals--a 14-month-old child and a 7-week-old infant… (More)
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1971
1971
Fifteen pregnant women with a 25 percent risk of delivering a child with Tay-Sachs disease were monitored by amniocentesis and… (More)
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