Taurochenodeoxycholic Acid

Known as: Ethanesulfonic acid, 2-(((3alpha,5beta,7alpha)-3,7-dihydroxy-24-oxocholan-24-yl)amino)-, Chenodeoxycholyltaurine, Acid, Taurochenodeoxycholic 
A bile salt formed in the liver by conjugation of chenodeoxycholate with taurine, usually as the sodium salt. It acts as detergent to solubilize fats… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1966-2018
051019662018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
The multidrug resistance protein ABCC4 (MRP4), a member of the ATP-binding cassette superfamily, mediates ATP-dependent… (More)
  • figure 1
  • figure 2
  • table 2
  • figure 3
  • figure 4
Is this relevant?
1999
1999
The aim of the present study was to identify the enzymes in human liver catalyzing hydroxylations of bile acids. Fourteen… (More)
Is this relevant?
1998
1998
BACKGROUND & AIMS Hydrophobic bile acids have been implicated in the pathogenesis of cholestatic liver injury. The hypothesis… (More)
Is this relevant?
1998
1998
The mechanisms by which inulin may elicit its lipid-lowering effect are not well elucidated. To examine the lipid-lowering… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
BACKGROUND & AIMS In sepsis, intrahepatic cholestasis occurs frequently, suggesting impaired hepatocyte transport of bile acids… (More)
Is this relevant?
1997
1997
Intraluminal bacteria, food intake, and bile play important roles in indomethacin-induced small intestinal inflammation in rats… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
BACKGROUND & AIMS The mechanisms causing liver injury in cholestatic diseases are unclear. The hypothesis that accumulation of… (More)
Is this relevant?
1993
1993
The mechanisms by which hydrophobic bile acids are toxic to the liver are unknown. To determine whether the generation of free… (More)
Is this relevant?
1983
1983
Bile acids are capable of disrupting the gastric and esophageal mucosal barriers and are known to differ in their ability to… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
1975
1975
The kinetics of disappearance of radioactivity from plasma after intravenous injection of radiolabeled bile acids was… (More)
Is this relevant?