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Taurochenodeoxycholic Acid

Known as: Ethanesulfonic acid, 2-(((3alpha,5beta,7alpha)-3,7-dihydroxy-24-oxocholan-24-yl)amino)-, Chenodeoxycholyltaurine, Acid, Taurochenodeoxycholic 
A bile salt formed in the liver by conjugation of chenodeoxycholate with taurine, usually as the sodium salt. It acts as detergent to solubilize fats… Expand
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
The multidrug resistance protein ABCC4 (MRP4), a member of the ATP-binding cassette superfamily, mediates ATP-dependent… Expand
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Highly Cited
2004
Highly Cited
2004
In this study, we investigated the effects of secretagogues and bile acids on the mitochondrial membrane potential of pancreatic… Expand
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1999
1999
The aim of the present study was to identify the enzymes in human liver catalyzing hydroxylations of bile acids. Fourteen… Expand
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1999
1999
To design a reliable 3D QSAR model of the intestinal Na(+)/bile acid cotransporter, we have used a training set of 17 inhibitors… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND & AIMS Hydrophobic bile acids have been implicated in the pathogenesis of cholestatic liver injury. The hypothesis… Expand
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Highly Cited
1998
Highly Cited
1998
The mechanisms by which inulin may elicit its lipid-lowering effect are not well elucidated. To examine the lipid-lowering… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND & AIMS In sepsis, intrahepatic cholestasis occurs frequently, suggesting impaired hepatocyte transport of bile acids… Expand
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1997
1997
Intraluminal bacteria, food intake, and bile play important roles in indomethacin-induced small intestinal inflammation in rats… Expand
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Highly Cited
1995
Highly Cited
1995
BACKGROUND & AIMS The mechanisms causing liver injury in cholestatic diseases are unclear. The hypothesis that accumulation of… Expand
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1975
1975
The kinetics of disappearance of radioactivity from plasma after intravenous injection of radiolabeled bile acids was… Expand
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