Taurine Lithocholate

Bile acids are well-recognized stimuli of glucagon-like peptide-1 (GLP-1) secretion. This action has been attributed to… Expand

Human multidrug-resistance protein (MRP) 4 transports cyclic nucleotides and when overproduced in mammalian cells mediates… Expand

Electrophysiological responses of goldfish olfactory receptor neurons (ORNs) and goldfish behavioral responses to polyamines were… Expand

BACKGROUND Taurolithocholate induced cholestasis is a well established model of drug induced cholestasis with potential clinical… Expand

Hydrophobic bile acids, which are known to be cytotoxic for hepatocytes, are retained in high amount in the liver during… Expand

Bile acid-induced apoptosis plays an important role in the pathogenesis of cholestatic liver disease, and its prevention is of… Expand

Bile acids (BA) enter cholangiocytes by the Na(+)-dependent apical BA transporter (ABAT). By this mechanism, taurocholate (TC… Expand

BACKGROUND & AIMS We have shown that taurocholate (TC) and taurolithocholate (TLC) interact in vitro with normal cholangiocytes… Expand

This paper describes the derivation of a bile salt monomeric hydrophobicity index that quantitatively defines the composite… Expand

To characterize the relative toxicity of different bile salts, isolated hepatocytes were incubated with different concentrations… Expand