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TXNRD1 wt Allele

Known as: TR, Trxr1, GRIM12 
Human TXNRD1 wild-type allele is located within 12q23-q24.1 and is approximately 135 kb in length. This allele, which encodes thioredoxin reductase 1… Expand
National Institutes of Health

Papers overview

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2016
2016
Metastasis is the most life threatening aspect of breast cancer. It is a multi-step process involving invasion and migration of… Expand
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2009
2009
We recently reported that the antineoplastic thiodioxopiperazine natural product chaetocin potently induces cellular oxidative… Expand
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Review
2006
Review
2006
Iron-sulfur (Fe/S) clusters are important cofactors of numerous proteins involved in electron transfer, metabolic and regulatory… Expand
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2006
2006
Previous studies demonstrate that the covalent modification of thioredoxin reductase (TrxR) by both endogenous and exogenous… Expand
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2006
2006
Certain selenoproteins such as GPX-1 (glutathione peroxidase-1) and TrxR1 (thioredoxin reductase-1) possess important antioxidant… Expand
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Highly Cited
2005
Highly Cited
2005
Thioredoxin reductase (TrxR) is a selenoprotein that catalyzes the reduction of the active site disulfide of thioredoxin (Trx… Expand
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Highly Cited
2003
Highly Cited
2003
The selenoprotein thioredoxin reductase (TrxR1) is an essential antioxidant enzyme known to reduce many compounds in addition to… Expand
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2003
2003
Thioredoxin reductases (TrxRs) catalyse the NADPH-dependent reduction of thioredoxin and play an important role in multiple… Expand
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Highly Cited
1997
Highly Cited
1997
Recent studies have suggested that coronary endothelial cells produce and release nitric oxide (NO), prostaglandin I2, and… Expand
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Highly Cited
1986
Highly Cited
1986
Summary1.The aim of this study was to identify neurons in the subesophageal ganglion of the medicinal leech which initiate… Expand
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