FAQ

TWIST1 gene

Known as: H-twist, SCS, TRANSCRIPTION FACTOR TWIST 
This gene plays a role in regulation of transcription and the inhibition of apoptosis. It is also involved in the control of morphogenesis during… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1972-2018
0102019722018

Related topics

Related topics

8 relations
Cell Differentiation processCraniosynostosisHomo sapiensMyogenesis
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Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
TWIST1 gene
Cell Differentiation process
dna binding
Homo sapiens
Craniosynostosis
Myogenesis

Papers overview

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2012
2012
TWIST1 is an ERK1/2 effector that promotes invasion and regulates MMP-1 expression in human melanoma cells.
Tumor cells often use developmental processes to progress toward advanced disease. The E-box transcription factor TWIST1 is… (More)
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Highly Cited
2008
Highly Cited
2008
Twist1 homodimers enhance FGF responsiveness of the cranial sutures and promote suture closure.
Haploinsufficiency of the transcription factor TWIST1 is associated with Saethre-Chotzen Syndrome and is manifested by… (More)
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2008
2008
TWIST1 Overexpression is Associated with Nodal Invasion and Male Sex in Primary Colorectal Cancer
TWIST1 is a basic helix–loop–helix (bHLH) transcription factor that has been involved in tumor progression and metastasis in… (More)
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Highly Cited
2007
Highly Cited
2007
Isolation and molecular profiling of bone marrow micrometastases identifies TWIST1 as a marker of early tumor relapse in breast cancer patients.
PURPOSE Micrometastatic cells detected in the bone marrow have prognostic significance in breast cancer. These cells are… (More)
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Highly Cited
2005
Highly Cited
2005
Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities
Autosomal dominant mutations in the gene encoding the basic helix-loop-helix transcription factor Twist1 are associated with limb… (More)
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Highly Cited
2005
Highly Cited
2005
Detection of hypermethylated genes in women with and without cervical neoplasia.
BACKGROUND DNA methylation changes are an early event in carcinogenesis and are often present in the precursor lesions of various… (More)
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1998
1998
Genetic heterogeneity of Saethre-Chotzen syndrome, due to TWIST and FGFR mutations.
Thirty-two unrelated patients with features of Saethre-Chotzen syndrome, a common autosomal dominant condition of… (More)
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1998
1998
The variable expressivity and incomplete penetrance of the twist-null heterozygous mouse phenotype resemble those of human Saethre-Chotzen syndrome.
Most targeted gene mutations are recessive and analyses of gene function often focus on homozygous mutant phenotypes. Here we… (More)
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1998
1998
A comprehensive screen for TWIST mutations in patients with craniosynostosis identifies a new microdeletion syndrome of chromosome band 7p21.1.
Mutations in the coding region of the TWIST gene (encoding a basic helix-loop-helix transcription factor) have been identified in… (More)
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Highly Cited
1997
Highly Cited
1997
Mutations in TWIST, a basic helix–loop–helix transcription factor, in Saethre-Chotzen syndrome
Saethre-Chotzen syndrome is one of the most common autosomal dominant disorders of craniosynostosis in humans and is… (More)
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