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TTK gene

Known as: TTK Protein Kinase Gene, MPS1, ESK, MOUSE, HOMOLOG OF 
This gene is involved in cell cycle checkpoint regulation.
National Institutes of Health

Related topics

Related topics

6 relations
Cell Cycle ControlCell divisionSerine/Threonine PhosphorylationTTK Protein Kinase
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TTK wt Allele

Papers overview

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Highly Cited
2010
Highly Cited
2010
Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine
Addition of reversine to dividing cells ejects Mad1 and the RZZ complex from unattached kinetochores and prevents resolution of… Expand
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Highly Cited
2009
Highly Cited
2009
Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination.
Eukaryotes possess mechanisms to limit crossing over during homologous recombination, thus avoiding possible chromosomal… Expand
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Highly Cited
2006
Highly Cited
2006
The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation.
The CDK11 (cyclin-dependent kinase 11) gene has an internal ribosome entry site (IRES), allowing the expression of two protein… Expand
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Highly Cited
2005
Highly Cited
2005
A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M
Fanconi anemia is a genetic disease characterized by genomic instability and cancer predisposition. Nine genes involved in… Expand
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Highly Cited
2004
Highly Cited
2004
Roles of Polo-like Kinase 1 in the Assembly of Functional Mitotic Spindles
BACKGROUND The stable association of chromosomes with both poles of the mitotic spindle (biorientation) depends on spindle… Expand
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Highly Cited
2002
Highly Cited
2002
Polycomb Group Gene rae28 Is Required for Sustaining Activity of Hematopoietic Stem Cells
The rae28 gene (rae28), also designated as mph1, is a mammalian ortholog of the Drosophila polyhomeotic gene, a member of… Expand
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Highly Cited
1999
Highly Cited
1999
Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen.
Small molecules that perturb specific protein functions are valuable tools for dissecting complex processes in mammalian cells. A… Expand
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Highly Cited
1998
Highly Cited
1998
Inactivation of the mitogen-activated protein kinase Mps1 from the rice blast fungus prevents penetration of host cells but allows activation of plant defense responses.
The rice blast fungus, Magnaporthe grisea, generates enormous turgor pressure within a specialized cell called the appressorium… Expand
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Highly Cited
1998
Highly Cited
1998
Wilson-Polyakov loop at finite temperature in large-N gauge theory and anti-de Sitter supergravity
Aspects of d = 4, At" = 4 superconformal U(N) gauge theory are studied at finite temperature. Utilizing dual description of large… Expand
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Highly Cited
1997
Highly Cited
1997
Super D-branes
We present a “kappa-symmetric” worldvolume action for all type II Dirichlet p-branes, 0≤p≤9, in a general type II supergravity… Expand
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