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TTC4 gene

Known as: MGC5097, FLJ41930, TETRATRICOPEPTIDE REPEAT DOMAIN-CONTAINING PROTEIN 4 
This gene plays a putative role in protein-membrane or protein-protein interactions.
National Institutes of Health

Related topics

Related topics

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Cell Proliferation Regulatory ProcessHomo sapiensNeoplastic Cell TransformationTTC3 gene

Papers overview

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2019
2019
MROH7‐TTC4 read‐through lncRNA suppresses vascular endothelial cell apoptosis and is upregulated by inhibition of ANXA7 GTPase activity
Apoptosis of vascular endothelial cells (VEC) is the main form of vascular injury that is closely linked to numerous… 
2014
2014
Two Distinct Nuclear Localization Signals in Mammalian MSL1 Regulate Its Function
MSL1 protein regulates global histone H4 acetylation at residue K16 in stem and cancer cells, through interaction with KAT8. The… 
2009
2009
Nuclear transport of protein TTC4 depends on the cell cycle
TTC4 (tetratricopeptide repeat domain protein 4) is a putative tumor suppressor involved in the transformation of melanocytes. At… 
2009
2009
Characterisation of Acropora AmTPR1, Drosophila Dpit47 andmouse TTC4 – a tetratricopeptide (TPR) gene family involvedin development and cell proliferation
The tetratricopeptide repeat (TPR) is a protein-protein interaction motif present in a variety of functionally unrelated proteins… 
2007
2007
Characterization of hampin/MSL1 as a node in the nuclear interactome.
2000
2000
TTC4, a novel candidate tumor suppressor gene at 1p31 is often mutated in malignant melanoma of the skin
A novel candidate tumor suppressor gene, TTC4, on chromosome 1p31 has been described recently. Since aberrations in this region… 
2000
2000
Genomic structure of the human tetratricopeptide repeat-containing gene, TTC4, from chromosome region 1p31 and mutation analysis in breast cancers.
Loss of heterozygosity (LOH) in 1p31 is a frequent genetic alteration in breast tumors indicating the site of a tumor suppressor… 
2000
2000
Assignment1 of TTC4 to human chromosome band 1p31.3 and a pseudogene TTC4P to 7p14→p13 by in situ hybridization
TTC4 is the fourth member of a human gene family that encodes proteins containing a conserved tetratricopeptide repeat motif. The… 
1999
1999
TTC4, a novel human gene containing the tetratricopeptide repeat and mapping to the region of chromosome 1p31 that is frequently deleted in sporadic breast cancer.
The 1p31 region shows loss of heterozygosity in up to 50% of human breast cancers, indicating the presence of a tumor suppressor… 
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