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TSPYL2 wt Allele

Known as: NP79, SE204, TSPX 
Human TSPYL2 wild-type allele is located in the vicinity of Xp11.2 and is approximately 6 kb in length. This allele, which encodes testis-specific Y… Expand
National Institutes of Health

Related topics

Related topics

5 relations
Cell Growth RegulationDNA Replication InhibitionXp11.2chromatin remodeling

Broader (1)

TSPYL2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Activity of the PI3K-δ,γ inhibitor duvelisib in a phase 1 trial and preclinical models of T-cell lymphoma.
Duvelisib (IPI-145) is an oral inhibitor of phosphatidylinositol 3-kinase (PI3K)-δ/γ isoforms currently in clinical development… Expand
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Highly Cited
2014
Highly Cited
2014
Long-term efficacy and safety of alemtuzumab in advanced primary cutaneous T-cell lymphomas.
BACKGROUND Alemtuzumab has been proposed as salvage therapy for refractory cutaneous T-cell lymphomas (CTCLs). Long-term follow… Expand
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Highly Cited
2013
Highly Cited
2013
Incidence and survival patterns of cutaneous T-cell lymphomas in the United States
Abstract Using the United States Surveillance, Epidemiology and End Results (SEER) 17 dataset, we examined incidence and survival… Expand
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Highly Cited
2009
Highly Cited
2009
Cutaneous lymphoma incidence patterns in the United States: a population-based study of 3884 cases.
There have been no prior large population-based studies focusing on cutaneous lymphomas (CL) in the United States. Using the… Expand
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Review
2009
Review
2009
Gonadoblastoma locus and the TSPY gene on the human Y chromosome.
The gonadoblastoma (GBY) locus is the only oncogenic locus on the human Y chromosome. It is postulated to serve a normal function… Expand
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Review
2009
Review
2009
Extracorporeal photopheresis: past, present, and future.
Extracorporeal photopheresis (ECP) is a leukapheresis-based therapy that uses 8-methoxypsoralen and ultraviolet A irradiation… Expand
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Highly Cited
2004
Highly Cited
2004
Transcriptional Modification by a CASK-Interacting Nucleosome Assembly Protein
CASK acts as a coactivator for Tbr-1, an essential transcription factor in cerebral cortex development. Presently, the molecular… Expand
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2004
2004
TSPY, the Candidate Gonadoblastoma Gene on the Human Y Chromosome, has a Widely Expressed Homologue on the X - Implications for Y Chromosome Evolution
TSPY, a candidate gene for a factor that promotes gonadoblastoma formation (GBY), is a testis-specific multicopy gene family in… Expand
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Highly Cited
2004
Highly Cited
2004
Adenovirus-mediated intralesional interferon-gamma gene transfer induces tumor regressions in cutaneous lymphomas.
Primary cutaneous lymphomas have been successfully treated with interferons (IFNs), counterbalancing the T-helper 2 (Th2)-skewing… Expand
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Highly Cited
2000
Highly Cited
2000
Diagnostic value of dominant T-cell clones in peripheral blood in 363 patients presenting consecutively with a clinical suspicion of cutaneous lymphoma.
It is now widely accepted that polymerase chain reaction (PCR) analysis of cutaneous T-cell clonality is of diagnostic value in… Expand
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