TSHR gene

Known as: THYROID-STIMULATING HORMONE RECEPTOR, Thyroid Stimulating Hormone Receptor Gene, LGR3 
This gene plays an important role in the regulation of thyroid cell metabolism.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1987-2017
010203019872017

Papers overview

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Review
2015
Review
2015
As most autoimmune diseases, inherited predisposition to Graves' disease (GD) is polygenic with the main contributory genes being… (More)
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2011
2011
A complex of the TSH receptor extracellular domain (amino acids 22-260; TSHR260) bound to a blocking-type human monoclonal… (More)
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2009
2009
Graves' disease (GD) is a common autoimmune disease (AID) that shares many of its susceptibility loci with other AIDs. The… (More)
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2008
2008
By proposing TSH as a key negative regulator of bone turnover, recent studies in TSH receptor (TSHR) null mice challenged the… (More)
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2007
2007
Hyperthyroidism in Graves' disease is caused by thyroid-stimulating autoantibodies to the TSH receptor (TSHR), whereas… (More)
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2005
2005
The development of autoimmune thyroid disease (AITD) is associated with autoantibodies directed against the thyroid stimulating… (More)
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2003
2003
Thyroid-stimulating hormone receptor (TSHR) expression is frequently silenced in epithelial thyroid cancers associated with… (More)
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2002
2002
Germline loss-of-function mutations of TSH receptor (TSHR) gene have been described in families with partial or complete TSH… (More)
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2002
2002
In this work we report a novel method to efficiently induce a murine model of Graves' hyperthyroidism. Inbred mice of different… (More)
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1996
1996
Graves disease is an autoimmune thyroid disease characterized by the presence of antibodies against the thyrotropin receptor… (More)
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