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TRP channels

 
National Institutes of Health

Papers overview

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2016
2016
The TRP Channels Pkd2, NompC, and Trpm Act in Cold-Sensing Neurons to Mediate Unique Aversive Behaviors to Noxious Cold in Drosophila
The basic mechanisms underlying noxious cold perception are not well understood. We developed Drosophila assays for noxious cold… Expand
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2016
2016
The involvement of TRP channels in sensory irritation: a mechanistic approach toward a better understanding of the biological effects of local irritants
Peripheral nerves innervating the mucosae of the nose, mouth, and throat protect the organism against chemical hazards. Upon… Expand
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Review
2015
Review
2015
Role of TRP channels in the cardiovascular system.
The transient receptor potential (TRP) superfamily consists of a large number of nonselective cation channels with variable… Expand
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2015
2015
Gene expressions of TRP channels in glioblastoma multiforme and relation with survival
Glioblastoma multiforme (GBM) is one of the most lethal forms of cancer in humans, with a median survival of 10 to 12 months… Expand
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Highly Cited
2014
Highly Cited
2014
Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the…
Epilepsy is the most common neurological disorder, with over 50 million people worldwide affected. Recent evidence suggests that… Expand
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Review
2014
Review
2014
Targeting TRP Channels For Novel Migraine Therapeutics
Migraine is increasingly understood to be a disorder of the brain. In susceptible individuals, a variety of "triggers" may… Expand
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2014
2014
Progressive degeneration of dopaminergic neurons through TRP channel-induced cell death.
Progressive neurodegenerative diseases are among the most frequently occurring aging-associated human pathologies. In a screen… Expand
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2014
2014
KCa3.1 modulates neuroblast migration along the rostral migratory stream (RMS) in vivo.
From the subventricular zone (SVZ), neuronal precursor cells (NPCs), called neuroblasts, migrate through the rostral migratory… Expand
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Review
2008
Review
2008
Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control.
New studies have revealed an essential role for TRPA1, a sensory neuronal TRP ion channel, in airway chemosensation and… Expand
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Highly Cited
2003
Highly Cited
2003
Formation of novel TRPC channels by complex subunit interactions in embryonic brain.
Mammalian short TRP channels (TRPCs) are putative receptor- and store-operated cation channels that play a fundamental role in… Expand
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