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TRIM63 protein, human

Known as: MuRF-1, MURF1 protein, human, RNF28 protein, human 
E3 ubiquitin-protein ligase TRIM63 (353 aa, ~40 kDa) is encoded by the human TRIM63 gene. This protein is involved in the degradation of myosin… 
National Institutes of Health

Related topics

Related topics

9 relations
E3 Ubiquitin-Protein Ligase TRAIP, humanEnzyme GeneLigase GeneTRIM63 gene

Broader (3)

Muscle ProteinsTripartite Motif Proteinsubiquitin-protein ligase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Role of Transcription Factors FoxO3 and Myogenin in Regulation of E3 Ligases MuRF-1 and MAFbx Expression in Rat Soleus at an Early Stage of Disuse Atrophy
Hypokinesia and gravitational unloading lead to skeletal muscle atrophy resulting from alterations in the balance between… 
2015
2015
운동 유형의 차이가 중년 흰쥐의 근 위축 인자에 미치는 영향
본 연구의 목적은 50주령의 중년 쥐를 대상으로 운동 유형에 따른 PGC-1α의 발현 정도가 근 위축 인자에 미치는 영향을 규명하는 것이다. 연구의 목적을 위해 50주령 수컷 쥐 30마리를 3… 
2014
2014
Atrogin-1 and MURF-1 signalling in human skeletal muscle
2013
2013
Investigation of wild-type and mycolactone-negative mutant Mycobacterium ulcerans on skeletal muscle: IGF-1 protects against mycolactone-induced muscle catabolism.
Buruli ulcer (BU), which is caused by Mycobacterium ulcerans (MU), is an endemic and neglected tropical disease that affects… 
2011
2011
Cachexia in heart disease: highlights from the ESC 2010
Cardiac cachexia is a co-morbidity that may develop in terminal stages of chronic heart failure (CHF). Up to 15% of ambulatory… 
2011
2011
Neuromyology III
This Special Section collects papers describing monitoring and experimental studies of neuromyopathies. The article by Pillen and… 
2009
2009
Hemin-induced Hmox-1 Associated With Downregulation Of Atrogin-1 And Murf-1 In C2c12 Myotubes: 635
2006
2006
Structural studies on protein scaffolds related to muscle physiology and disease : the titin filament, its associated component MuRF-1 and nuclear LAP2[alpha]
The titin molecule has a length of overµm and functions as a colossal protein scaffold in the muscle sarcomere. Up to 90% of its… 
2002
2002
Peroxide perturbations
2002
2002
Clash of the titin
![Graphic][1] Sarcomere thick filaments (white) are disrupted by inhibition of titin–MURF-1 binding (right). The sarcomere is… 
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