Skip to search formSkip to main contentSkip to account menu

TRIM63 protein, human

Known as: MuRF-1, MURF1 protein, human, RNF28 protein, human 
E3 ubiquitin-protein ligase TRIM63 (353 aa, ~40 kDa) is encoded by the human TRIM63 gene. This protein is involved in the degradation of myosin… 
National Institutes of Health

Related topics

Related topics

9 relations
E3 Ubiquitin-Protein Ligase TRAIP, humanEnzyme GeneLigase GeneTRIM63 gene

Broader (3)

Muscle ProteinsTripartite Motif Proteinsubiquitin-protein ligase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Skeletal muscle-specific Prmt1 deletion causes muscle atrophy via deregulation of the PRMT6-FOXO3 axis
ABSTRACT Protein arginine methyltransferases (PRMTs) have emerged as important regulators of skeletal muscle metabolism and… 
2017
2017
miR-4417 Targets Tripartite Motif-Containing 35 (TRIM35) and Regulates Pyruvate Kinase Muscle 2 (PKM2) Phosphorylation to Promote Proliferation and Suppress Apoptosis in Hepatocellular Carcinoma…
Background MicroRNAs (miRNAs) are a class of small non-coding RNAs that are strongly involved in various types of carcinogenesis… 
Highly Cited
2015
Highly Cited
2015
Angiotensin-(1-7) decreases skeletal muscle atrophy induced by angiotensin II through a Mas receptor-dependent mechanism.
Skeletal muscle atrophy is a pathological condition characterized by the loss of strength and muscle mass, an increase in myosin… 
Review
2013
Review
2013
Atrogin-1, MuRF-1, and sarcopenia
Sarcopenia is one of the leading causes of disability in the elderly. Despite the growing prevalence of sarcopenia, the molecular… 
Highly Cited
2013
Highly Cited
2013
Attenuated Increase in Maximal Force of Rat Medial Gastrocnemius Muscle after Concurrent Peak Power and Endurance Training
Improvement of muscle peak power and oxidative capacity are generally presumed to be mutually exclusive. However, this may not be… 
Highly Cited
2012
Highly Cited
2012
Exercise Training Attenuates MuRF-1 Expression in the Skeletal Muscle of Patients With Chronic Heart Failure Independent of Age: The Randomized Leipzig Exercise Intervention in Chronic Heart Failure…
Background— Muscle wasting occurs in both chronic heart failure (CHF) and normal aging and contributes to exercise intolerance… 
Highly Cited
2007
Highly Cited
2007
Olig2-Regulated Lineage-Restricted Pathway Controls Replication Competence in Neural Stem Cells and Malignant Glioma
Highly Cited
2007
Highly Cited
2007
Myocardial expression of Murf-1 and MAFbx after induction of chronic heart failure: Effect on myocardial contractility.
Highly Cited
2005
Highly Cited
2005
MURF-1 and MURF-2 target a specific subset of myofibrillar proteins redundantly: towards understanding MURF-dependent muscle ubiquitination.
Highly Cited
2001
Highly Cited
2001
Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain.
The giant myofibrillar protein titin contains within its C-terminal region a serine-threonine kinase of unknown function. We have… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)