TRIM Motif

Known as: TRIM Domain, RBCC/TRIM Motif, Tripartite Motif 
The TRIM motif includes three cysteine-rich zinc-binding domains, a RING finger, a B-box, and a coiled-coil region. The order of the sub-domains is… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Innate immunity conferred by the type I interferon is critical for antiviral defense. To date only a limited number of tripartite… (More)
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Highly Cited
2011
Highly Cited
2011
SUMOylation governs numerous cellular processes and is essential to most eukaryotic life. Despite increasing recognition of the… (More)
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Highly Cited
2010
Highly Cited
2010
Antibodies provide effective antiviral immunity despite the fact that viruses escape into cells when they infect. Here we show… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Tripartite motif (TRIM) proteins constitute a family of proteins that share a conserved tripartite architecture. The… (More)
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Highly Cited
2007
Highly Cited
2007
The human tripartite motif (TRIM) family comprises 70 members, including HIV restriction factor TRIM5alpha and disease-associated… (More)
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Review
2007
Review
2007
The control of retroviral infection by antiviral factors referred to as restriction factors has become an exciting area in… (More)
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Highly Cited
2007
Highly Cited
2007
The TRIM family is composed of multi-domain proteins that display the Tripartite Motif (RING, B-box and Coiled-coil) that can be… (More)
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Highly Cited
2007
Highly Cited
2007
Retinoic-acid-inducible gene-I (RIG-I; also called DDX58) is a cytosolic viral RNA receptor that interacts with MAVS (also called… (More)
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Highly Cited
2005
Highly Cited
2005
The tripartite motif 5alpha protein (TRIM5alpha) is one of several factors expressed by mammalian cells that inhibit retrovirus… (More)
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Highly Cited
2001
Highly Cited
2001
A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a… (More)
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