TREM2 gene

Known as: Trem2b, Triggering Receptor Expressed On Myeloid Cells 2 Gene, Trem2c 
This gene plays a role in the activation of immune responses.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Alzheimer's disease (AD) is the sixth leading cause of death in the United States and the most common cause of dementia in the… (More)
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Highly Cited
2016
Highly Cited
2016
Genetic variants of TREM2, a protein expressed selectively by microglia in the brain, are associated with Alzheimer's disease (AD… (More)
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Review
2014
Review
2014
Late-onset Alzheimer's disease (AD) is a sporadic disorder with increasing prevalence in aging. The ɛ4 allele of Apolipoprotein E… (More)
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Highly Cited
2014
Highly Cited
2014
Recent genome-wide association studies linked variants in TREM2 to a strong increase in the odds of developing Alzheimer’s… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Homozygous loss-of-function mutations in TREM2, encoding the triggering receptor expressed on myeloid cells 2 protein… (More)
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Highly Cited
2012
Highly Cited
2012
OBJECTIVE To identify new genes and risk factors associated with frontotemporal dementia (FTD). Several genes and loci have been… (More)
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Highly Cited
2008
Highly Cited
2008
Alzheimer's disease (AD) is characterized by extracellular deposits of amyloid-beta protein which attract dense clusters of… (More)
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Highly Cited
2005
Highly Cited
2005
UNLABELLED Deficiency of the signaling adapter protein DAP12 or its associated receptor TREM2 is associated with abnormal OC… (More)
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Highly Cited
2003
Highly Cited
2003
Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), Nasu-Hakola disease, is a globally… (More)
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