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TRDMT1 wt Allele

Known as: tRNA Aspartic Acid Methyltransferase 1 wt Allele, MHSAIIP, M.HsaIIP 
Human TRDMT1 wild-type allele is located in the vicinity of 10p15.1 and is approximately 60 kb in length. This allele, which encodes tRNA (cytosine… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Here we show that the cytosine-5 methyltransferase DNMT2 controls retrotransposon silencing in Drosophila somatic cells. In… Expand
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Highly Cited
2009
Highly Cited
2009
The cytosine analogues azacytidine and decitabine are currently being developed as drugs for epigenetic cancer therapy. Although… Expand
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Highly Cited
2008
Highly Cited
2008
Although their amino acid sequences and structure closely resemble DNA methyltransferases, Dnmt2 proteins were recently shown by… Expand
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Highly Cited
2007
Highly Cited
2007
The roles of DNA methyltransferase-2 (DNMT2) enzymes are controversial; whether DNMT2 functions primarily as a nuclear DNA… Expand
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Highly Cited
2006
Highly Cited
2006
The sequence and the structure of DNA methyltransferase-2 (Dnmt2) bear close affinities to authentic DNA cytosine… Expand
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Highly Cited
2003
Highly Cited
2003
ABSTRACT While CpG methylation can be readily analyzed at the DNA sequence level in wild-type and mutant cells, the actual DNA… Expand
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Highly Cited
2003
Highly Cited
2003
The methylation status of Drosophila DNA has been discussed controversially over a long time. Recent evidence has provided strong… Expand
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Highly Cited
2001
Highly Cited
2001
To evaluate the significance of alterations in DNA methylation during human hepatocarcinogenesis, we examined levels of mRNA for… Expand
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Highly Cited
1998
Highly Cited
1998
We have shown previously that de novo methylation activities persist in mouse embryonic stem (ES) cells homozygous for a null… Expand
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Highly Cited
1998
Highly Cited
1998
Trace levels of 5-methylcytosine persist in the DNA of mouse embryonic stem cells that are homozygous for null mutations in Dnmt1… Expand
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