TRDMT1 wt Allele

Known as: tRNA Aspartic Acid Methyltransferase 1 wt Allele, MHSAIIP, M.HsaIIP 
Human TRDMT1 wild-type allele is located in the vicinity of 10p15.1 and is approximately 60 kb in length. This allele, which encodes tRNA (cytosine… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2017
0519982017

Papers overview

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Highly Cited
2012
Highly Cited
2012
The function of cytosine-C5 methylation, a widespread modification of tRNAs, has remained obscure, particularly in mammals. We… (More)
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Highly Cited
2009
Highly Cited
2009
Here we show that the cytosine-5 methyltransferase DNMT2 controls retrotransposon silencing in Drosophila somatic cells. In… (More)
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Highly Cited
2007
Highly Cited
2007
The roles of DNA methyltransferase-2 (DNMT2) enzymes are controversial; whether DNMT2 functions primarily as a nuclear DNA… (More)
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Highly Cited
2006
Highly Cited
2006
The sequence and the structure of DNA methyltransferase-2 (Dnmt2) bear close affinities to authentic DNA cytosine… (More)
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Highly Cited
2003
Highly Cited
2003
While CpG methylation can be readily analyzed at the DNA sequence level in wild-type and mutant cells, the actual DNA (cytosine-5… (More)
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2002
2002
We have shown recently that about half of the human TGCTs(3) reveal DNA copy number increases affecting two distinct regions on… (More)
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Highly Cited
2001
Highly Cited
2001
To evaluate the significance of alterations in DNA methylation during human hepatocarcinogenesis, we examined levels of mRNA for… (More)
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Highly Cited
2001
Highly Cited
2001
DNMT2 is a human protein that displays strong sequence similarities to DNA (cytosine-5)-methyltransferases (m(5)C MTases) of both… (More)
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Highly Cited
1998
Highly Cited
1998
We have shown previously that de novo methylation activities persist in mouse embryonic stem (ES) cells homozygous for a null… (More)
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Highly Cited
1998
Highly Cited
1998
Trace levels of 5-methylcytosine persist in the DNA of mouse embryonic stem cells that are homozygous for null mutations in Dnmt1… (More)
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