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TRC105
Known as:
Anti-Endoglin Chimeric Monoclonal Antibody TRC105
A human/murine chimeric monoclonal antibody directed against endoglin (CD105) with potential antiangiogenic and antineoplastic activities. Anti…
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National Institutes of Health
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Related topics
Related topics
3 relations
Broader (1)
Monoclonal Antibodies
NCIt Antineoplastic Agent Terminology
antigen binding
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Endoglin interacts with VEGFR 2 to promote angiogenesis
Hongyu Tian
,
Jennifer J. Huang
,
+4 authors
G. Blobe
2018
Corpus ID: 113399354
Endoglin, a TGF-b coreceptor predominantly expressed in endothelial cells, plays an important role in vascular development and…
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2017
2017
Bevacizumab Plus TRC105 Failed to Improve PFS in Refractory, Metastatic RCC
L. Lawrence
2017
Corpus ID: 149767846
TRC105, a monoclonal antibody against endoglin, failed to improve progression-free survival when added to bevacizumab compared…
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2016
2016
TRC105 Gets Orphan Drug Status for Soft-Tissue Sarcoma
D. Levitan
2016
Corpus ID: 155720143
The FDA has granted orphan drug designation for the novel agent known as TRC105, in development by Tracon Pharmaceuticals, for…
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2016
2016
Abstract 2048: Pharmacodynamic biomarker studies of TRC105 anti-endoglin (CD105) antibody revealed anti-angiogenic activity associated with CD105 depletion
Liang Cao
,
F. Karzai
,
+5 authors
W. Dahut
2016
Corpus ID: 57701162
Introduction: CD105 is involved in normal vascular development. It is over expressed on the surface of proliferating vascular…
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2016
2016
TRAXAR study: a randomized phase 2 trial of axitinib and TRC105 versus axitinib alone in patients with advanced or metastatic renal cell carcinoma (mRCC)
T. Choueiri
,
N. Agarwal
,
+6 authors
C. Theuer
2016
Corpus ID: 79010621
2013
2013
CARACTERÍSTICAS DE DISEÑO DE UN GLOBO SONDA RECUPERABLE Y REUTILIZABLE Design features of a recoverable and reusable probe globe
Julio Enoc
,
Parra Villamarin
,
+5 authors
José de Caldas
2013
Corpus ID: 111808032
Magister en Ciencias de la Informacion y las Comunicaciones – Universidad Distrital “Francisco Jose de Caldas”, Ingeniero…
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2013
2013
89Zr-Labeled anti-CD105 (endoglin) chimeric monoclonal antibody TRC105 linked to IRDye 800CW
A. Chopra
2013
Corpus ID: 99178226
2012
2012
66Ga-Labeled PEGylated nano-graphene oxide (GO) covalently linked to NOTA-conjugated anti-CD105 (endoglin) chimeric monoclonal antibody TRC105
A. Chopra
2012
Corpus ID: 138443094
The CD105 antigen (endoglin) is a hypoxia-inducible, 180-kDa, disulfide-linked, homodimeric transmembrane glycoprotein that is a…
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2012
2012
Purpose: Our goal was to explore nano-graphene for in vivo tumor targeting and quantitatively evaluate the pharmacokinetics and tumor targeting efficacy through PET imaging, using 64Cu and 66Ga as…
2012
Corpus ID: 34499795
ID: 17654 Title: In Vivo Targeting and Imaging of Tumor Vasculature with Radiolabeled, Antibody-Conjugated Nano-Graphene Purpose…
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2012
2012
[Table, IRDye800CW-anti-CD105 TRC105 chimeric monoclonal antibody].
K. Leung
2012
Corpus ID: 88787500