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TRAIL receptor activity

Known as: tumor necrosis factor-related apoptosis-inducing ligand receptor 
Combining with the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) and transmitting the signal from one side of the plasma… Expand
National Institutes of Health

Papers overview

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2017
2017
Recent evidences indicate that triple-negative breast cancer (TNBC) cells with a mesenchymal phenotype show a basal activation of… Expand
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2013
2013
The herbal flavonoid quercetin inhibits the growth of various cancer cells, but how it affects human cancer cells, particularly… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Lexatumumab (HGS-ETR2) is a fully human agonistic mAb to the tumor necrosis factor-related apoptosis-inducing ligand… Expand
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Highly Cited
2010
Highly Cited
2010
Objective: To identify antemortem CSF diagnostic biomarkers that can potentially distinguish between the 2 main causes of… Expand
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2009
2009
Purpose: Glioblastomas are among the most lethal neoplasms, with a median survival of <1 year. Modulation of the proteasome… Expand
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Review
2007
Review
2007
Apoptosis is a cardinal feature of liver injury. Death receptors are major mediators of the apoptotic pathway in the liver and… Expand
Highly Cited
2006
Highly Cited
2006
Induction of tumor cell resistance to therapeutics has been a major obstacle in cancer therapy. Targeting of the death receptors… Expand
2006
2006
The tumor necrosis factor–related apoptosis-inducing ligand receptor modulates apoptotic response by binding to the proapoptotic… Expand
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2004
2004
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in tumor but not normal cells, thus providing… Expand
Highly Cited
2002
Highly Cited
2002
Studies with mouse embryo fibroblasts deficient for the BCL-2 family multidomain proapoptotic proteins BAX and BAK have revealed… Expand
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