FAQ

TRAIL binding

Known as: Apo-2L binding 
Interacting selectively and non-covalently with TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family… (More)

Topic mentions per year

Topic mentions per year

1999-2017
012319992017

Related topics

Related topics

2 relations

Broader (2)

TRAIL receptor activitydeath receptor binding

Related mentions per year

Related mentions per year

1982-2017
19801990200020102020
TRAIL binding
death receptor binding
TRAIL receptor activity

Papers overview

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2016
2016
Layer by layer assembly of albumin nanoparticles with selective recognition of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).
Crosslinked albumin nanoparticles which loaded with doxorubicin (DOX) were fabricated with tumor necrosis factor-related… (More)
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2015
2015
Variants of Osteoprotegerin Lacking TRAIL Binding for Therapeutic Bone Remodeling in Osteolytic Malignancies.
UNLABELLED Osteolytic bone damage is a major cause of morbidity in several metastatic pathologies. Current therapies using… (More)
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2015
2015
Cell Death and Survival Variants of Osteoprotegerin Lacking TRAIL Binding for Therapeutic Bone Remodeling in Osteolytic Malignancies
Osteolytic bone damage is amajor cause ofmorbidity in several metastatic pathologies. Current therapies using bisphosphonates… (More)
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2013
2013
Osteoprotegerin (OPG) activates integrin, focal adhesion kinase (FAK), and Akt signaling in ovarian cancer cells to attenuate TRAIL-induced apoptosis
BACKGROUND Resistance to apoptosis is a major problem in ovarian cancer (OC) and correlates with poor prognosis. Osteoprotegerin… (More)
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2010
2010
Novel HTS Strategy Identifies TRAIL-Sensitizing Compounds Acting Specifically Through the Caspase-8 Apoptotic Axis
Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) is potentially a very important therapeutic as it shows… (More)
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2009
2009
Human monomeric antibody fragments to TRAIL-R1 and TRAIL-R2 that display potent in vitro agonism.
Apoptosis through the TRAIL receptor pathway can be induced via agonistic IgG to either TRAIL-R1 or TRAIL-R2. Here we describe… (More)
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2005
2005
Homomeric and heteromeric interactions of the extracellular domains of death receptors and death decoy receptors.
Death receptors (DRs) can induce apoptosis by oligomerization with TRAIL, whereas death decoy receptors (DcRs) cannot, due to… (More)
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2003
2003
Preparation and characterization of a set of monoclonal antibodies to TRAIL and TRAIL receptors DR4, DR5, DcR1, and DcR2.
The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo 2L) is a novel cytotoxic ligand belonging to TNF… (More)
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Highly Cited
2001
Highly Cited
2001
Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways
Tumor necrosis (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family of cytokines that promotes apoptosis… (More)
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Highly Cited
1999
Highly Cited
1999
Functional analysis of TRAIL receptors using monoclonal antibodies.
mAbs were generated against the extracellular domain of the four known TNF-related apoptosis-inducing ligand (TRAIL) receptors… (More)
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