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TPX2 protein, human

Known as: Protein Fls353, p100, Differentially Expressed In Lung Cells 
Targeting protein for Xklp2 (747 aa, ~86 kDa) is encoded by the human TPX2 gene. This protein plays a role in the formation of mitotic spindles.
National Institutes of Health

Related topics

Related topics

14 relations
Cell Cycle ControlCell Proliferation Regulatory ProcessGTP BindingGenes, Regulator

Broader (3)

Cell Cycle ProteinsMicrotubule-Associated ProteinsNuclear Proteins

Papers overview

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2018
2018
Role of PLK1 signaling pathway genes in gastrointestinal stromal tumors
In previous studies by the authors, aurora kinase A (AURKA) was demonstrated as an independent poor prognostic marker for the… 
2017
2017
p100 functions as a metastasis activator and is targeted by tumor suppressing microRNA‐320a in lung cancer
Lung cancer is among the most frequently diagnosed types of cancer worldwide, with high morbidity and mortality. Metastasis… 
2012
2012
Aberrant microtubule organization in dividing root cells of p60-katanin mutants
Aberrant microtubule organization has been recently recorded in dividing root cells of fra2 and lue1 p60-katanin Arabidopsis… 
2007
2007
Negative regulation of TCR signaling by NF-kappaB2/p100.
The positive regulation of the NF-kappaB-signaling pathway in response to TCR stimulation has been well-studied. However, little… 
2006
2006
[TPX2 expression and its significance in squamous cell carcinoma of lung].
OBJECTIVE To study the expression of targeting protein for Xklp2 (TPX2) and its significance in squamous cell carcinoma (SCC) of… 
2005
2005
Essential role of IkappaB kinase alpha in the constitutive processing of NF-kappaB2 p100.
Processing of NF-kappaB2 precursor protein p100 to generate p52 is tightly controlled, which is important for proper function of… 
2003
2003
Regulation of NF-κB2/p100 processing by its nuclear shuttling
Processing of the NF-κB2 precursor protein p100 to generate p52 is an important step of NF-κB regulation. This proteolytic event… 
2003
2003
Regulation of NF-kappaB2/p100 processing by its nuclear shuttling.
Processing of the NF-kappaB2 precursor protein p100 to generate p52 is an important step of NF-kappaB regulation. This… 
1991
1991
Purification of p100, a protein antigenically related to the signal transducing G proteins Gt and Gi. Evidence for an adaptin-like protein.
1990
1990
A novel 100 kDa protein, localized to receptor-enriched endosomes, is immunologically related to the signal-transducing guanine-nucleotide-binding proteins Gt and Gi.
Antisera raised against the C-terminus decapeptide of the alpha-subunit of the retinal guanine-nucleotide-binding protein (G… 
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