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TPCN1 gene

Known as: KIAA1169, TWO-PORE CHANNEL 1, two pore segment channel 1 
 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Plants exhibit rapid, systemic signaling systems that allow them to coordinate physiological and developmental responses… Expand
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2014
2014
Four-domain voltage-gated Ca2+ and Na+ channels (CaV, NaV) underpin nervous system function and likely emerged upon intragenic… Expand
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Highly Cited
2012
Highly Cited
2012
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a messenger that regulates calcium release from intracellular acidic… Expand
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2011
2011
NAADP is a potent second messenger that mobilizes Ca(2+) from acidic organelles such as endosomes and lysosomes. The molecular… Expand
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Highly Cited
2009
Highly Cited
2009
Ca2+ mobilization from intracellular stores represents an important cell signalling process that is regulated, in mammalian cells… Expand
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Highly Cited
2007
Highly Cited
2007
The putative two-pore Ca(2+) channel TPC1 has been suggested to be involved in responses to abiotic and biotic stresses. We show… Expand
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Review
2007
Review
2007
The central vacuole is the largest Ca2+ store in a mature plant cell. Ca2+ release from this store contributes to Ca2+-mediated… Expand
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Highly Cited
2006
Highly Cited
2006
PURPOSE Papillary thyroid carcinomas are associated with nonoverlapping activating mutations of RET, NTRK, RAS and BRAF, which… Expand
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Highly Cited
2005
Highly Cited
2005
Cytosolic free calcium ([Ca2+]cyt) is a ubiquitous signalling component in plant cells. Numerous stimuli trigger sustained or… Expand
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Highly Cited
2001
Highly Cited
2001
The gene encoding voltage-gated channel with high affinity for Ca(2+) permeation has not been cloned from plants. In the present… Expand
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