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TPA 023

Known as: TPA-023, TPA023 
National Institutes of Health

Papers overview

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Review
2012
Review
2012
Review
2012
  • P. Skolnick
  • Trends in pharmacological sciences
  • 2012
  • Corpus ID: 13932634
Review
2011
Review
2011
  • J. Atack
  • Current topics in medicinal chemistry
  • 2011
  • Corpus ID: 37882457
The prototypic benzodiazepines, such as diazepam, are not only anxiolytic but also produce sedation. These effects are mediated… 
Highly Cited
2010
Highly Cited
2010
Abuse-liability-related effects of subtype-selective GABAA modulators were explored relative to the prototypic benzodiazepine… 
Review
2008
Review
2008
  • J. Atack
  • CNS neuroscience & therapeutics
  • 2008
  • Corpus ID: 2328179
TPA023 and α5IA are structurally related compounds that selectively modulate certain GABAA receptor subtypes. Hence, TPA023 has… 
Highly Cited
2007
Highly Cited
2007
TPA023, a GABAA α2,3 αsubtype-selective partial agonist, is expected to have comparable anxiolytic efficacy as benzodiazepines… 
Highly Cited
2006
Highly Cited
2006
7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine (TPA023) is a…