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TP53BP2 wt Allele

Known as: Tumor Protein P53 Binding Protein, 2 Gene, Tumor Protein P53-Binding Protein-2 Gene, PPP1R13A 
Human TP53BP2 wild-type allele is located in the vicinity of 1q42.1 and is approximately 66 kb in length. This allele, which encodes apoptosis… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Apoptosis-stimulating protein of p53-2 (ASPP2) induces apoptosis by promoting the expression of pro-apoptotic genes via binding… Expand
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Highly Cited
2011
Highly Cited
2011
Type I strains of Helicobacter pylori (Hp) possess a pathogenicity island, cag, that encodes the effector protein cytotoxin… Expand
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Highly Cited
2010
Highly Cited
2010
UNLABELLED The ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region-containing protein (ASPP) family of… Expand
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Highly Cited
2010
Highly Cited
2010
Cell polarity plays a key role in the development of the central nervous system (CNS). Interestingly, disruption of cell polarity… Expand
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Highly Cited
2010
Highly Cited
2010
The Hippo pathway regulates organ size by controlling both cell proliferation and apoptosis. TAZ functions as a transcriptional… Expand
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Highly Cited
2008
Highly Cited
2008
ASPP1 and ASPP2 are activators of p53-dependent apoptosis, whereas iASPP is an inhibitor of p53. Binding assays showed… Expand
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Highly Cited
2007
Highly Cited
2007
The transcription factor p53 is a critical component in the normal cell’s response to damage owing to cellular stresses such as… Expand
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Highly Cited
2006
Highly Cited
2006
ASPP2 stimulates the apoptotic function of the p53 family in vivo. We show here that ASPP2-/- pups died before weaning. This… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT We recently showed that ASPP1 and ASPP2 stimulate the apoptotic function of p53. We show here that ASPP1 and ASPP2 also… Expand
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Highly Cited
1999
Highly Cited
1999
Nuclear factor κB (NF-κB) is a transcription factor that controls the expression of many cellular and viral genes. The p65 (RelA… Expand
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