TP53 wt Allele

Known as: p53 gene, P53, TRP53 
Human TP53 wild-type allele is located in the vicinity of 17p13.1 and is approximately 19 kb in length. This allele, which encodes cellular tumor… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Anticancer chemotherapy drugs challenge hematopoietic tissues to regenerate but commonly produce long-term sequelae. Chemotherapy… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Most personalized cancer care strategies involving DNA sequencing are highly reliant on acquiring sufficient fresh or… (More)
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2013
2013
Oxidative stress is caused by an imbalance between the production of reactive oxygen species (ROS) and the ability of an organism… (More)
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2011
2011
Notch receptors and their ligands have crucial roles in development and tumorigenesis. We present evidence demonstrating the… (More)
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Highly Cited
2009
Highly Cited
2009
We screened exon 4 of the gene isocitrate dehydrogenase 1 (NADP+), soluble (IDH1) for mutations in 596 primary intracranial… (More)
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2009
2009
Trp53 loss of function has previously been shown to rescue tissue maintenance and developmental defects resulting from DNA damage… (More)
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2007
2007
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. HCC patients frequently present with disease… (More)
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Highly Cited
2004
Highly Cited
2004
We reported previously that transcription factor nuclear factor (NF)-kappaB is constitutively activated in human and murine… (More)
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Review
2002
Review
2002
The human p53 tumor suppressor gene TP53 is mutated at a high frequency in sporadic breast cancer, and Li-Fraumeni syndrome… (More)
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2000
2000
The slow folding of a single tryptophan-containing mutant of barstar has been studied in the presence of 2 M urea at 10 degrees C… (More)
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