TP53 Gene Mutation

Known as: p53 Mutation 
A change in the nucleotide sequence of the TP53 gene.
National Institutes of Health

Papers overview

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Review
2005
Review
2005
PURPOSE The aims of the TP53 Colorectal Cancer (CRC) International Collaborative Study were to evaluate the possible associations… (More)
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Highly Cited
1997
Highly Cited
1997
The PTEN gene, located on 10q23, has recently been implicated as a candidate tumor suppressor gene in brain, breast and prostate… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Mutations of the p53 gene are associated with a poor prognosis in several types of cancer. We investigated the… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND p53 gene mutation and p53 protein accumulation are common in human cancer. However, their clinical significance is… (More)
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Highly Cited
1994
Highly Cited
1994
We analyzed the prognostic value of p53 mutations for response to chemotherapy and survival in acute myeloid leukemia (AML… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND/AIMS In long-term extensive ulcerative colitis, aneuploidy occurs earlier and loss of heterozygosity for p53 (p53 LOH… (More)
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Highly Cited
1993
Highly Cited
1993
The p53 gene was analyzed in tumor specimens obtained from 52 patients with various types of carcinoma of the thyroid gland by a… (More)
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Highly Cited
1993
Highly Cited
1993
A G:C-->T:A mutational hotspot at codon 249 of the p53 tumor suppressor gene has previously been identified in hepatocellular… (More)
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Highly Cited
1992
Highly Cited
1992
We investigated the immunocytochemical staining and immunoblotting characteristics of 33 different p53 mutant proteins identified… (More)
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Highly Cited
1992
Highly Cited
1992
The human brain tumor, astrocytoma, typically progresses through three histopathologically defined stages with the passage of… (More)
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