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TP-508

Known as: TP 508, TP508, thrombin peptide TP508 
National Institutes of Health

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rusalatide acetate

Papers overview

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2015
2015
Novel Regenerative Peptide TP508 Mitigates Radiation-Induced Gastrointestinal Damage By Activating Stem Cells and Preserving Crypt Integrity
In recent years, increasing threats of radiation exposure and nuclear disasters have become a significant concern for the United… 
2009
2009
Thrombin related peptide TP508 promoted fracture repair in a mouse high energy fracture model
BackgroundThrombin related peptide (TP508) is a 23 amino-acid synthetic peptide that represents a portion of the receptor-binding… 
2007
2007
Thrombin peptide Chrysalin® stimulates healing of diabetic foot ulcers in a placebo‐controlled phase I/II study
Thrombin and thrombin peptides play a role in initiating tissue repair. The potential safety and efficacy of TP508 (Chrysalin… 
Review
2006
Review
2006
Thrombin peptide TP508 stimulates cellular events leading to angiogenesis, revascularization, and repair of dermal and musculoskeletal tissues.
The thrombin peptide, TP508, also known as Chrysalin (OrthoLogic, Tempe, Arizona), is a twenty-three-amino-acid peptide that… 
Highly Cited
2005
Highly Cited
2005
Thrombin peptide (TP508) promotes fracture repair by up‐regulating inflammatory mediators, early growth factors, and increasing angiogenesis
2004
2004
The thrombin peptide, TP508, enhances cytokine release and activates signaling events
Highly Cited
2002
Highly Cited
2002
Controlled release of an osteogenic peptide from injectable biodegradable polymeric composites.
Review
2000
Review
2000
Thrombin peptide, TP508, stimulates angiogenic responses in animal models of dermal wound healing, in chick chorioallantoic membranes, and in cultured human aortic and microvascular endothelial cells…
Highly Cited
2000
Highly Cited
2000
Acceleration of full‐thickness wound healing in normal rats by the synthetic thrombin peptide, TP508
Thrombin is an essential factor in hemostasis, inflammation, and tissue repair. The synthetic thrombin peptide, TP508, binds to… 
1999
1999
Thrombin peptide, TP508, induces differential gene expression in fibroblasts through a nonproteolytic activation pathway.
Prior studies have shown that synthetic peptides representing the domain of thrombin responsible for high-affinity binding to… 
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